Biology, Computing, and the History of Molecular Sequencing

1. Introduction: An Historical Approach to Sequencing
Miguel García-Sancho

Part I. Emergence: Frederick Sanger’s Pioneering Techniques (1943–1977)

2. The Sequence of Insulin and the Configuration of a New Biochemical Form of Work (1943–1962)
Miguel García-Sancho

3. From Chemical Degradation to Biological Replication (1962–1977)
Miguel García-Sancho

Part II. Mechanisation — 1: Computing and the Automation of Sequence Reconstruction (1962–1987)

4. Sequencing Software and the Shift in the Practice of Computation
Miguel García-Sancho

5. Sequence Databases and the Emergence of ‘Information Engineers’
Miguel García-Sancho

Part III. Mechanisation — 2: The Sequencer and the Automation of Sequence Construction (1980–2000)

6. A New Approach to Sequencing at Caltech
Miguel García-Sancho

7. The Commercialisation of the DNA Sequencer
Miguel García-Sancho

8. Conclusions: A Long History of Practices
Miguel García-Sancho

Nyckelord: History, History of Science, Popular Science, general, History of Medicine, Modern History, Social History, Biochemistry, general