Sirtuins

1. Biochemistry and Enzymology of Sirtuins
Yue Yang, Anthony A. Sauve

2. NAD+ as a Pharmacological Tool to Boost Sirtuin Activity
Riekelt H. Houtkooper

3. Protein Lysine Acylation: Abundance, Dynamics and Function
Olga Pougovkina, Vincent C. J. Boer

4. SIRT1 in Metabolic Health and Disease
Marie Boutant, Carles Cantó

5. Deacetylation by SIRT3 Relieves Inhibition of Mitochondrial Protein Function
Peter Chhoy, Kristin A. Anderson, Kathleen A. Hershberger, Frank K. Huynh, Angelical S. Martin, Eoin McDonnell, Brett S. Peterson, Laura A. Starzenski, Donald S. Backos, Kristofer S. Fritz, Matthew D. Hirschey

6. SIRT5 Reveals Novel Enzymatic Activities of Sirtuins
Bin He, Hening Lin

7. Diverse Roles for SIRT6 in Mammalian Healthspan and Longevity
Bernadette M. M. Zwaans, William Giblin, David B. Lombard

8. Sirtuins in Cancer – Emerging Role as Modulators of Metabolic Reprogramming
Jaewon J. Lee, Karina N. Gonzalez Herrera, Marcia C. Haigis

9. Sirtuins as Metabolic Modulators of Muscle Plasticity
Keir Menzies, Julien Francisco Zaldivar-Jolissaint, Johan Auwerx

10. Sirtuins and Aging
Carles Cantó, Riekelt H. Houtkooper

11. Sirtuins and the Circadian Clock: Epigenetic and Metabolic Crosstalk
Selma Masri, Marina Maria Bellet, Paolo Sassone-Corsi

12. Sirtuin Activation by Small Molecules
Hassina Massudi, Lindsay E. Wu, David A. Sinclair

13. Sirtuins: A Future Perspective
Brian K. Kennedy

Avainsanat: Biomedicine, Cancer Research, Metabolic Diseases, Diabetes, Molecular Medicine