Signal Transduction in Cancer Metastasis

1. Overview of Signal Transduction in Tumor Metastasis
Wen-Sheng Wu, Jia-Ru Wu

2. Microenvironment Triggers EMT, Migration and Invasion of Primary Tumor via Multiple Signal Pathways
Wen-Sheng Wu, Chi-Tan Hu

3. The ERK1/2 MAP Kinase Signaling Pathway in Tumor Progression and Metastasis
Laure Voisin∗, Stéphanie Duhamel∗, Sylvain Meloche

4. Mitogen-Activated Protein Kinase-Activated Protein Kinases and Metastasis
Alexey Shiryaev, Marijke Ghelue, Ugo Moens

5. Grb2 and Other Adaptor Proteins in Tumor Metastasis
Alessio Giubellino, Praveen R. Arany

6. The Role of ROS Signaling in Tumor Progression
Wen-Sheng Wu, Jia-Ru Wu

7. Signal Cross Talks for Sustained MAPK Activation and Cell Migration Mediated by Reactive Oxygen Species: The Involvement in Tumor Progression
Chi-Tan Hu, Jia-Ru Wu, Wen-Sheng Wu

8. Insights into the Dynamics of Focal Adhesion Protein Trafficking in Invasive Cancer Cells and Clinical Implications
Moulay A. Alaoui-Jamali, Krikor Bijian, Panagiota Toliopoulos

9. Notch Signaling in Cancer Metastasis
Pingyu Zhang, Patrick A. Zweidler-McKay

10. New Concepts on the Critical Functions of Cancer- and Metastasis-Initiating Cells in Treatment Resistance and Disease Relapse: Molecular Mechanisms, Signaling Transduction Elements and Novel Targeting Therapies
Murielle Mimeault, Surinder K. Batra

11. Involvement of Lipid Rafts in Growth Factor Receptors-Mediated Signaling for Cancer Metastasis
Samir Kumar Patra

12. Cadherin-Catenin Signaling in Ovarian Cancer Progression
Lydia W.T. Cheung, Carman K.M. Ip, Alice S.T. Wong

13. PTP4A3, a Signal Molecule Deregulated in Uveal Melanoma Metastasis
Cécile Laurent, Jérôme Couturier, Xavier Sastre-Garau, Laurence Desjardins, Emmanuel Barillot, Sophie Piperno-Neumann, Simon Saule

14. Signal Transduction Pathways Involved in Hepatocarcinogenesis and Metastasis of Hepatoma
Rajagopal N. Aravalli

Avainsanat: Biomedicine, Cancer Research, Molecular Medicine, Cytokines and Growth Factors, Receptors, Cell Biology