Cell Line Development

1. Use of MAR Elements to Increase the Production of Recombinant Proteins
Cori Gorman, Salina Arope, Mélanie Grandjean, Pierre-Alain Girod, Nicolas Mermod

2. Expression Engineering – The IE2 Promoter/Enhancer from Mouse CMV
Markus O. Imhof, Philippe Chatellard, Michel Kobr, Renata Pankiewicz, Valérie Duverger, Léonard Bagnoud, Christophe Sauvage, Christine Mossu

3. Defeating Randomness – Targeted Integration as a Boost for Biotechnology
L. Gama-Norton, P. Riemer, U. Sandhu, K. Nehlsen, R. Schucht, H. Hauser, D. Wirth

4. Importance of Genetic Environment for Recombinant Gene Expression
Alan J. Dickson

5. Expression Vector Engineering for Recombinant Protein Production
Helen Kim, John Laudemann, Jennitte Stevens, Michelle Wu

6. Cell Xpress™ Applications in Development and Characterization of Biopharmaceutical Recombinant Protein Producing Cell Lines
Jennifer R. Cresswell, Nan Lin, Genova A. Richardson, Kevin J. Kayser

7. Selection Methods for High-Producing Mammalian Cell Lines
S. M. Browne, M. Al-Rubeai

8. Engineering Mammalian Cells for Recombinant Monoclonal Antibody Production
Sarah L. Davies, David C. James

9. Engineering Cell Function by RNA Interference
Joseph A. Gredell, Hemant K. Kini, S. Patrick Walton

10. Apoptosis and Autophagy Cell Engineering
Chaya Mohan, Yeon-Gu Kim, Gyun Min Lee

11. Glycoengineering and Modeling of Protein N-Glycosylation
Sandra V. Bennun, Frederick J. Krambeck, Michael J. Betenbaugh

12. Engineering the Secretory Pathway in Mammalian Cells
Ren-Wang Peng, Martin Fussenegger

Avainsanat: Biomedicine, Biomedicine general, Cell Biology, Genetic Engineering, Biochemistry, general