Kataoka, Kazunori
Non-viral Gene Therapy
1..Molecules for Gene Therapy
1. Recent Progress in Non-viral Gene Delivery
Christine C. Conwell, Leaf Huang
2. Physical Chemistry of DNA-Carrier Complexes
Kenichi Yoshikawa, Yuko Yoshikawa
3. Liposomes
Kazuo Maruyama
4. Polymeric Gene Carriers
Tomoko Hashimoto, Tetsuji Yamaoka
5. Development of a Supramolecular Nanocarrier for Gene Delivery Based on Cationic Block Copolymers
Yuichi Yamasaki, Woo-Dong Jang, Nobuhiro Nishiyama, Naoki Kanayama, Kazunori Kataoka
6. Chitosan
Mayu Hashimoto, Zhihong Yang, Yohei Koya, Toshinori Sato
7. Dendrimers as DNA Carriers
Hidetoshi Arima
8. Use of Synthetic Peptides for Non-viral Gene Delivery
Takuro Niidome, Yoshiki Katayama
9. An Oligonucleotide Carrier Based on ß-1,3-Glucans
Kazuo Sakurai, Seiji Shinkai
10. Biological and Chemical Hybrid Vectors
Mahito Nakanishi
2..Controlled Gene Delivery
11. Pharmacokinetics of Gene Delivery in Cells
Hidetaka Akita, Ikramy A. Khalil, Kentaro Kogure, Hideyoshi Harashima
12. Active DNA Release from Complexes
Takeshi Nagasaki
13. Controlled Release of DNA Using Thermoresponsive Polymers
Masayuki Yokoyama
14. Active Transport of Exogenous Genes into the Nucleus
Takeshi Kawazu, Takeshi Nagasaki
15. Controlled Intracellular Localization of Oligonucleotides by Chemical Conjugation
Takanori Kubo, Rumiana Bakalova, Zhivko Zhelev, Hideki Ohba, Masayuki Fujii
16. Functional Nucleotide Sequences Capable of Promoting Non-viral Genetic Transfer
Osam Mazda, Tsunao Kishida
17. Shielding of Cationic Charge of the DNA Complex to Avoid Nonspecific Interactions for In Vivo Gene Delivery
Yoshiyuki Koyama
18. In Vivo Gene Transfer by Ligand-Modified Gene Carriers
Shigeru Kawakami, Mitsuru Hashida
19. Optimizing Polyplexes into Synthetic Viruses for Tumor-Targeted Gene Therapy
Ernst Wagner, Julia Kloeckner, Manfred Ogris
20. Gene Transfer and Target Diseases
Mariko Harada-Shiba
21. Clinical Trials Using Non-viral Gene Delivery Systems
Hironobu Yanagie
3..Current Protocols of Gene Delivery
22. Evaluation of Size and Zeta Potential of DNA/Carrier Complexes
Yoshiyuki Hattori, Mitsuru Hashida
23. Observation of DNA/Carrier Complexes Under Fluorescence Microscopy
Tomoko Ito, Yoshiyuki Koyama, Kenichi Yoshikawa
24. Synthesis of Chemically Modified Chitosan and a Study of Its Gene Transfection Efficiency
Taku Satoh
25. Newly Designed DNA Fragments for Gene Correction
Hiroyuki Kamiya, Hiroyuki Tsuchiya, Hideyoshi Harashima
26. Evaluation of Gene Expression In Vivo After Intravenous and Intraportal Administration of Lipoplexes
Tatsuya Okuda, Shigeru Kawakami, Mitsuru Hashida
27. Evaluation by Southern Blot Hybridization of DNA Administered with a Gene Carrier to Organs
Takahito Kawano, Takuro Niidome
28. Evaluation of the Immune Response After Administration of Plasmid DNA-Non-viral Vector Complexes
Fuminori Sakurai, Yoshinobu Takakura, Mitsuru Hashida
29. Gateway RNAi
Knut R. Madden, Adam N. Harris, Jennifer M. Kilzer, Heidi L. Welchin, Peter J. Welch
4..Design of Genes Based on Current RNA Technology
30. Design of Intracellularly Active Ribozymes and siRNAs
Makoto Miyagishi, Kazunari Taira
31. RNAi-Based Inhibition Specific for Mutant Alleles in Autosomal Dominant Diseases: Sequence-Dependent and -Independent Discrimination of Mutant and Wild-Type Alleles by siRNA
Takanori Yokota
32. In Vivo RNA Interference: Another Tool in the Box?
Silvère Petit, Emmanuel Valentin, Kader Thiam
33. Suppression of Gene Expression via Chromatin Remodeling and the siRNA-Induced Silencing of Transcription
Hiroaki Kawasaki, Yoko Fukuda, Kazunari Taira, Kevin V. Morris
34. Intracellular Delivery of Nucleic Acids: Differences Between Transfection and siFection Reflect Differences Between DNA and RNA, and Between Oligodeoxynucleotides and Oligonucleotides
Michael Keller, Andrew D. Miller
35. In Vivo Antitumor Activity of a New Cationic Liposome siRNA Complex
Junichi Yano, Gerald E. Smyth, Kazuko Hirabayashi, Tadaaki Ohgi
36. Enhancing RNAi with Synthetic RNA Duplexes
Dong-Ho Kim, Mark A. Behlke, Scott D. Rose, Mi-Sook Chang, Sangdun Choi, John J. Rossi
DRM-restrictions
Printing: not available
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Avainsanat: SCIENCE / Life Sciences / Biology / General SCI008000
- Tekijä(t)
- Kataoka, Kazunori
- Niidome, Takuro
- Taira, Kazunari
- Julkaisija
- Springer
- Julkaisuvuosi
- 2005
- Kieli
- en
- Painos
- 1
- Kategoria
- Eksaktit luonnontieteet
- Tiedostomuoto
- E-kirja
- eISBN (PDF)
- 9784431278795