Programmed Cells from Basic Neuroscience to Therapy

1. iPS Cell Technology and Disease Research: Issues To Be Resolved
Rudolf Jaenisch

2. Therapeutic Somatic Cell Reprogramming by Nuclear Transfer
Stan Wang, John B. Gurdon

3. Induction of Neural Lineages from Mesoderm and Endoderm by Defined Transcription Factors
Marius Wernig

4. Proposing a Model for Studying Primate Development Using Induced Pluripotent Stem Cells
Maria C. N. Marchetto, Alysson R. Muotri, Fred H. Gage

5. HTT Evolution and Brain Development
Chiara Zuccato, Elena Cattaneo

6. Human Pluripotent and Multipotent Stem Cells as Tools for Modeling Neurodegeneration
Jerome Mertens, Philipp Koch, Oliver Brüstle

7. Human Stem Cell Approaches to Understanding and Treating Alzheimer’s Disease
Lawrence S. B. Goldstein

8. Potential of Stem Cell-Derived Motor Neurons for Modeling Amyotrophic Lateral Sclerosis (ALS)
Derek H. Oakley, Gist F. Croft, Hynek Wichterle, Christopher E. Henderson

9. Using Pluripotent Stem Cells to Decipher Mechanisms and Identify Treatments for Diseases That Affect the Brain
Marc Peschanski, Cécile Martinat

10. Modeling Autism Spectrum Disorders Using Human Neurons
Alysson Renato Muotri

11. On the Search for Reliable Human Aging Models: Understanding Aging by Nuclear Reprogramming
Ignacio Sancho-Martinez, Emmanuel Nivet, Juan Carlos Izpisua Belmonte

Avainsanat: Biomedicine, Neurosciences, Stem Cells, Neurology