Leading Pharmaceutical Operational Excellence

Part I. Introduction

1. Introduction to Leading Operational Excellence: Making OPEX a Competitive Weapon
Thomas Friedli, Prabir Basu

2. OPEX: A Definition
Thomas Friedli, Daniel Bellm

3. The History of OPEX in the Pharmaceutical Industry
Thomas Friedli, Jürgen Werani

4. The Current State of Operational Excellence Implementation: 10 Years of Benchmarking
Thomas Friedli, Nikolaus Lembke, Uli Schneider, Saskia Gütter

5. Leading the Advance in Regulatory Science
Nuala Calnan

6. A Look to the Environment and the Impact on OPEX
Thomas Friedli, Daniel Bellm

7. Barriers and Success Factors in Managing Operational Excellence
Thomas Friedli, Daniel Bellm

Part II. Leading Operational Excellence: Outstanding Practices

8. From Process Stabilization to Plant Network Performance: Pfizer’s Journey to Operational Excellence
Colin Seller, Richard Davis

9. Ten Years with OPEX as a Brand: cLEAN© in Novo Nordisk Product Supply
Kasper Mejlvang

10. Lean in Novartis Pharma: Sustainability Through a Five Step Deployment Methodology
Steve Dreamer, Pav Niewiarowski

11. Abbott Pharmaceuticals Journey of Business Excellence Standards
Valentin Starke, Joseph Kumor

12. Structuring and Implementing an Operational Excellence Program from Scratch in the Biotech Industry
Wright Troy

13. Implementing an OE Strategy on Plant Level
Jürgen Werani, Volker Pfahlert, Kai Reimers, Gert Diederich

14. Winning the “Facility of the Year” - Award with an Indian Plant
Sanjit Singh Lamba

15. Succeeding at the ‘Harder’ Side of Change: The ‘ABCs’ of High-Performance Behavior
Ned Morse, Nick South, Gideon Walter

16. Structures of Operational Excellence Initiatives
Thomas Friedli, Nikolaus Lembke

17. Preventive Process Stabilization by Integrated Process Development
Thomas Friedli, Reto Ziegler

18. Matching Problems with Tools
Thomas Friedli, Christian Mänder, Daniel Bellm

19. Introducing Complexity in the Equation: How Pfizer Made Complexity on a Plant Level Transparent
Colin Seller, Richard Davis, Matthias Götzfried, Thomas Friedli

20. Knowledge Exchange in Production Networks: Operational Excellence Multiplied
Simone Thomas, Fabian Liebetrau, Thomas Friedli

Part III. Leading Operational Excellence: Outstanding Leadership

21. Leadership Principles & Operational Excellence
Thomas Friedli, Jürgen Werani

22. Transformational Leadership - Shaping the Future of the Biopharmaceutical Industry
Andy Crossman

23. Making Operational Excellence a Priority at Every Level
David Hampton

24. How Do We Create Leadership Pull for Operational Excellence?
Paul Docherty

25. Leadership Characteristics for a Sustainable OPEX-Implementation
Uta Walkhoff

26. Leading Operational Excellence in a Global Company
Mark McColgan

27. Leading an Operational Excellence Program at a Geographic Area Level
Jürgen Werani

28. Continuous Improvement: A Path Towards Excellence
Kim Sandell, Jesper Eriksson, Karin Eriksson, Maria Stigell Warnström, Kirsti Gjellan

Part IV. Gaining the Future

29. The Future of Pharmaceutical Manufacturing
Prabir Basu, Thomas Friedli, Daniel Bellm

30. Managing Global Pharmaceutical Manufacturing Networks
Thomas Friedli, Fabian Liebetrau, Richard Luetzner

Avainsanat: Economics/Management Science, Production/Logistics/Supply Chain Management, Business Strategy/Leadership, Pharmaceutical Sciences/Technology, Operation Research/Decision Theory, Management/Business for Professionals