Protein Quality Control in Neurodegenerative Diseases

1. The regulation and function of the heat shock response
Eric Guisbert, Richard I. Morimoto

2. The endoplasmic reticulum unfolded protein response and neurodegeneration
David Ron

3. Proteostasis and the aging pathways
Ian Nicastro, Andrew Dillin

4. The membrane sources of macroautophagy
Daniel J. Klionsky, Melinda A. Lynch-Day, Jiefei Geng, Wei-Lien Yen

5. Selective autophagy in cellular quality control
Susmita Kaushik, Ana Maria Cuervo

6. Quality control of proteins and organelles by autophagy
Noboru Mizushima

7. The role of the co-chaperone BAG3 in selective macroautophagy: implications for aging and disease
Christian Behl

8. Predicting fates in models of neurodegenerative disease: longitudinal measures of protein homeostasis in live neurons
Steven Finkbeiner

9. Therapeutic potential of longevity modulators as neuroprotective targets in neurodegenerative disease
Rafael Vazquez-Manrique, Cendrine Tourette, Christian Neri

10. The interplay between the chaperonin TRiC and N-terminal region of Huntingtin mediates Huntington’s Disease aggregation and pathogenesis
Koning Shen, Judith Frydman

Avainsanat: Biomedicine, Neurosciences, Neurochemistry, Molecular Medicine