Clinical Hepatology

Part I. Structure and Function of the Liver

1. Embryonic Development
Henryk Dancygier

2. Gross Anatomy
Henryk Dancygier

3. Microscopic Anatomy
Henryk Dancygier

4. Hepatic Circulation
Henryk Dancygier

5. Hepatocellular Transport
Henryk Dancygier

6. Hepatic Metabolism
Henryk Dancygier, Uta Merle, Wolfgang Stremmel, Claus Niederau

7. Formation and Secretion of Bile and Bilirubin Metabolism
Ulrich Leuschner

8. Hepatic Biotransformation
Henryk Dancygier

9. Functional Heterogeneity and Metabolic Zonation
Henryk Dancygier

10. Liver Cell Hydration and Cell Function
Dieter Häussinger

11. The Liver as an Immune Organ
Henryk Dancygier

12. Aging and the Liver
Henryk Dancygier

13. Hepatic Regeneration
Henryk Dancygier

Part II. Pathophysiology and Morphology of Liver Injury

14. Free Radicals, Reactive Oxygen Species, Oxidative and Endoplasmic Reticulum Stress
Henryk Dancygier, Peter Schirmacher

15. Hypoxic Liver Injury
Henryk Dancygier, Peter Schirmacher

16. Reperfusion Injury
Henryk Dancygier, Peter Schirmacher

17. Drug-Induced and Toxic Liver Injury
Henryk Dancygier, Peter Schirmacher

18. Immune Mediated Liver Injury
Henryk Dancygier, Peter Schirmacher

19. Endotoxin Mediated Liver Injury
Henryk Dancygier, Peter Schirmacher

20. Cholestasis-Induced Liver Injury
Henryk Dancygier, Peter Schirmacher

21. Metal-Induced Liver Injury
Henryk Dancygier, Peter Schirmacher

22. Radiation-Induced Liver Damage
Henryk Dancygier, Peter Schirmacher

23. Liver Cell Degeneration and Cell Death
Henryk Dancygier, Peter Schirmacher

24. Cellular Adaptation, Intracellular Inclusions and Deposits
Henryk Dancygier, Peter Schirmacher

25. Necroinflammatory Reaction
Henryk Dancygier, Peter Schirmacher

26. Cholestatic Reaction
Henryk Dancygier, Peter Schirmacher

27. Granulomatous Reaction
Henryk Dancygier, Peter Schirmacher

28. Fibrogenic Reaction
Henryk Dancygier, Peter Schirmacher

29. Histopathological Scoring Systems
Thomas Longerich, Peter Schirmacher

30. Clinical Scoring Systems
Henryk Dancygier

Part III. Evaluation of the Patient with Hepatobiliary Disease

31. History
Henryk Dancygier, Jason N. Rogart

32. Symptoms
Henryk Dancygier, Jason N. Rogart

33. Physical Examination
Henryk Dancygier, Jason N. Rogart

34. Basic Laboratory Parameters
Henryk Dancygier

35. Tests of Liver Function
Henryk Dancygier

36. Autoantibodies
Henryk Dancygier

37. Ultrasonography
Christoph F. Dietrich

38. Computed Tomography and Magnetic Resonance Imaging
Sukru M. Erturk, Esra Cay, Pablo R. Ros

39. Nuclear Imaging
Burkhard Riemann, Otmar Schober

40. Endoscopic Retrograde and Percutaneous Transhepatic Cholangiography
Henryk Dancygier, Frank Stenschke, Jason N. Rogart

41. Cholangioscopy
Jason N. Rogart, Frank Stenschke

42. Endoscopic Ultrasonography
Henryk Dancygier, Andreas Niedenthal, Jason N. Rogart

43. Percutaneous Liver Biopsy
Christian P. Strassburg

44. Transvenous Liver Biopsy
Ilan S. Weisberg, Samuel H. Sigal, Robert S. Brown

45. Laparoscopy
Philip Hilgard, Guido Gerken

46. Measurement of Portal Pressure
Henryk Dancygier

47. Sphincter of Oddi Manometry
Hans-Dieter Allescher

48. Approach to the Patient with Upper Abdominal Pain
Henryk Dancygier, Jason N. Rogart

49. Approach to the Patient with Abnormal Liver Enzymes
Henryk Dancygier, Jason N. Rogart

50. Approach to the Patient with Hepatomegaly
Henryk Dancygier, Jason N. Rogart

51. Approach to the Patient with Focal Liver Lesions
Henryk Dancygier, Jason N. Rogart

52. Approach to the Patient with Cholestasis and Jaundice
Henryk Dancygier, Jason N. Rogart

53. Approach to the Patient with Portal Hypertension
Henryk Dancygier, Jason N. Rogart

54. Approach to the Patient with Ascites
Henryk Dancygier, Jason N. Rogart

Avainsanat: Medicine & Public Health, Hepatology, Gastroenterology, Endocrinology, Medical Biochemistry, Pathology