Aquaporins

I. Aquaporin Protein Structure and Selectivity Mechanisms

1. Discovery of the Aquaporins and Development of the Field
Jennifer M. Carbrey, Peter Agre

2. The AQP Structure and Functional Implications
Thomas Wspalz, Yoshinori Fujiyoshi, Andreas Engel

3. Dynamics and Energetics of Permeation Through Aquaporins. What Do We Learn from Molecular Dynamics Simulations?
Jochen S. Hub, Helmut Grubmüller, Bert L. Groot

4. In Vitro Analysis and Modification of Aquaporin Pore Selectivity
Eric Beitz, Dana Becker, Julia Bülow, Christina Conrad, Nadine Fricke, Amornrat Geadkaew, Dawid Krenc, Jie Song, Dorothea Wree, Binghua Wu

II. Aquaporin Function in Mammalian Water Homeostasis

5. Aquaporins in the Kidney
Tae-Hwan Kwon, Jakob Nielsen, Hanne B. Møller, Robert A. Fenton, Søren Nielsen, Jørgen Frøkiær

6. Regulation of Aquaporin-2 Trafficking
Pavel I. Nedvetsky, Grazia Tamma, Sven Beulshausen, Giovanna Valenti, Walter Rosenthal, Enno Klussmann

7. Role of Aquaporin-4 in Cerebral Edema and Stroke
Zsolt Zador, Shirley Stiver, Vincent Wang, Geoffrey T. Manley

8. Aquaporins as Potential Drug Targets for Meniere's Disease and its Related Diseases
Taizo Takeda, Daizo Taguchi

9. Aquaporins in Secretory Glands and their Role in Sjögren's Syndrome
Christine Delporte

III. Aquaporin Glycerol Permeability in Mammalian Physiology

10. Skin Aquaporins: Function in Hydration, Wound Healing, and Skin Epidermis Homeostasis
Mathieu Boury-Jamot, Jean Daraspe, Frédéric Bonté, Eric Perrier, Sylvianne Schnebert, Marc Dumas, Jean-Marc Verbavatz

11. Function of Aquaporin-7 in the Kidney and the Male Reproductive System
Eisei Sohara, Shinichi Uchida, Sei Sasaki

12. Role of Aquaporin-7 and Aquaporin-9 in Glycerol Metabolism; Involvement in Obesity
Norikazu Maeda, Toshiyuki Hibuse, Tohru Funahashi

13. New Members of Mammalian Aquaporins: AQP10–AQP12
Kenichi Ishibashi

IV. Aquaporin Functions Apart from Water and Glycerol Transport

14. Structural Function of MIP/Aquaporin 0 in the Eye Lens; Genetic Defects Lead to Congenital Inherited Cataracts
Ana B. Chepelinsky

15. pH Regulated Anion Permeability of Aquaporin-6
Masato Yasui

16. Aquaglyceroporins and Metalloid Transport: Implications in Human Diseases
Hiranmoy Bhattacharjee, Barry P. Rosen, Rita Mukhopadhyay

17. Ammonia and Urea Permeability of Mammalian Aquaporins
Thomas Litman, Rikke Søgaard, Thomas Zeuthen

18. Knock-Out Models Reveal New Aquaporin Functions
Alan S. Verkman

V. Towards Therapeutic Use of Aquaporins

19. Design, Synthesis and Assaying of Potential Aquaporin Inhibitors
Rose Haddoub, Michael Rützler, Aélig Robin, Sabine L. Flitsch

20. Aquaporin-1 Gene Transfer to Correct Radiation-Induced Salivary Hypofunction
Bruce J. Baum, Changyu Zheng, Ana P. Cotrim, Linda McCullagh, Corinne M. Goldsmith, Jaime S. Brahim, Jane C. Atkinson, R. James Turner, Shuying Liu, Nikolay Nikolov, Gabor G. Illei

Avainsanat: Biomedicine, Pharmacology/Toxicology, Human Physiology, Life Sciences, general, Nephrology, Neurology, Hematology