Lipidomics: Technologies and Applications

Focusing on the practical applications, this user-oriented guide presents current technologies and strategies for systems-level lipid
analysis, going beyond basic research to concentrate on commercial uses of lipidomics in biomarker and diagnostic development, as well
as within pharmaceutical drug discovery and development. The editor and authors have experience of the most recent analytical instruments and techniques, allowing them to provide here first-hand practical experience for newcomers to the field. The first half of the book covers current methodologies, ranging from global to targeted lipidomics and shotgun approaches, while the second part discusses the role of lipidomics in biomedical and pharmaceutical research, covering such diverse fields as inflammation, metabolic syndrome, cardiovascular and neurological disease. Both small and large-scale, high-throughput approaches are discussed, resulting in an invaluable source for academic and industrial research and development.

Avainsanat: lipidomics, lipid-analysis, lipid analysis, lipids, biomarkers, bioanalytics, diagnostics, pharmaceuticals, drug discovery, drug development, targeted lipidomics, pharmaceutical research, biomedical research, inflammation, metabolic syndrome, cardiovasular disease, neurological disease, large-scale, high-throughput, research and development, systems-level lipd analysis, lipid species, Kim Ekroos, Zora Biosciences, lipid biomarker discovery, cellular recognition, lipidome, bioscience, moleuclar lipidomics, validated clinical diagnostics, analytical lipid outputs, molecular lipids, structurally defined molecular lipids, lipids in cells, cellular lipid distribution, Multidimensional Mass Spectrometry-Based Shotgun Lipidomics, High-Throughput Molecular Lipidomics, Targeted Lipidomics, Sphingolipidomics, Structural Lipidomics, untargeted fragmentation, imaging lipids, lipid informatics, lipids in human disease, lipoprotein biology, lipoproteinomics, normolipidemic, phospholipids, Phosphatidylcholine, Lysophosphatidylcholine, Mediator Lipidomics, inflammation research, PUFA-Derived Lipid Mediators, LC-ESI-MS/MS-Based Lipidomics, Mediator Lipidomics in Inflammation and Resolution, Lipidomics for Elucidation of Metabolic Syndrome and Related Lipid Metabolic Disorder, Mass Spectrometry in Lipidomics, lipidomic data processing, lipid search, Oxidized Phospholipids, Bioactive Acidic Phospholipids, Lipid Molecular Species, Lipidomics in Atherosclerotic Vascular Disease, Lipoproteins, Lipidomics in Efficacy and Safety Measurements, Lipid Metabolism in Neurodegenerative Diseases, brain lipids, Phospholipases, Tumor Mitochondrial Lipidome and Respiratory Bioenergetic Insufficiency, Lipidomics for Pharmaceutical Research, Genomics & Proteomics, Analytical Chemistry, Genomics & Proteomics, Analytical Chemistry