Abdel-Meguid, Sherin S.
Protein Crystallography in Drug Discovery
Here, researchers from leading pharmaceutical companies present valuable first-hand information, much of it published for the first time. They discuss strategies to derive high-resolution structures for such important target protein classes as kinases or proteases, as well as selected examples of successful protein crystallographic studies. A special section on recent methodological developments, such as for high-throughput crystallography and microcrystallization, is also included.
A valuable companion for crystallographers involved in protein structure determination as well as drug developers pursuing the structure-based approach for use in their daily work.
Avainsanat: SCIENCE / Chemistry / Industrial & Technical SCI013060
- Tekijä(t)
- Abdel-Meguid, Sherin S.
- Babine, Robert E.
- Folkers, Gerd
- Kubinyi, Hugo
- Mannhold, Raimund
- Julkaisija
- John Wiley and Sons, Inc.
- Julkaisuvuosi
- 2006
- Kieli
- en
- Painos
- 1
- Sarja
- Methods and Principles in Medicinal Chemistry
- Sivumäärä
- 278 sivua
- Kategoria
- Tekniikka, energia, liikenne
- Tiedostomuoto
- E-kirja
- eISBN (PDF)
- 9783527606351
- Painetun ISBN
- 9783527306787