5-HT2A Receptors in the Central Nervous System

Part I. Properties and Distribution of the 5-HT2AR

1. Pharmacological Analysis in Favour of a Physiological Role for the Constitutive Activity of 5-HT2A Receptors in Learning
Philippe Deurwaerdère, Guillaume Drutel, Giuseppe Giovanni

2. βArrestins: Ligand-Directed Regulators of 5-HT2A Receptor Trafficking and Signaling Events
Cullen L. Schmid, Laura M. Bohn

3. 5-HT2A Receptor Heterodimerization
Sylwia Łukasiewicz, Ewa Błasiak, Marta Dziedzicka-Wasylewska

4. Brain Distribution
Cristiano Bombardi

5. PET Imaging of the 5-HT2A Receptor System: A Tool to Study the Receptor’s In Vivo Brain Function
Matthias M. Herth, Gitte M. Knudsen

Part II. 5-HT2AR Related Brain Functions

6. Serotonergic Receptor 5-HT2A in the Cardiosympathovagal System
M. Kermorgant, A. Pavy-Le Traon, J. M. Senard, D. N. Arvanitis

7. Crosstalk Between 5-HT2A and mGlu2 Receptors: Implications in Schizophrenia and Its Treatment
José L. Moreno, Javier González-Maeso

8. Schizophrenia
Anna Castañé, Albert Adell

9. Role of Serotonin-2A Receptors in Pathophysiology and Treatment of Depression
Lucia Moravčíková, Kristína Csatlósová, Barbora Ďurišová, Katarína Ondáčová, Michaela Pavlovičová, Ľubica Lacinová, Eliyahu Dremencov

10. Brain Circuits Regulated by the 5-HT2A Receptor: Behavioural Consequences on Anxiety and Fear Memory
L. Moulédous, P. Roullet, Bruno P. Guiard

11. 5-HT2A/2B/2C Receptors, Memory and Therapeutic Targets
Alfredo Meneses, Rossana Nieto-Vera, Rosa María Anaya-Jiménez

12. 5-HT2A Receptors in the Basal Ganglia
Cristina Miguelez, Teresa Morera-Herreras, Philippe Deurwaerdère

13. The Involvement of 5-HT2A Receptor in the Regulation of Sleep and Wakefulness, and the Potential Therapeutic Use of Selective 5-HT2A Receptor Antagonists and Inverse Agonists for the Treatment of an Insomnia Disorder
Jaime M. Monti, Seithikurippu R. Pandi Perumal, D. Warren Spence, Pablo Torterolo

14. 5-HT2A Receptors and Pain
Christine Courteix, Amandine Dupuis, Pierre-Yves Martin, Benoit Sion

15. 5-HT2A Receptors in Eating Disorders
Philip Gorwood, Laurence Lanfumey, Odile Viltart, Nicolas Ramoz

16. Role of Serotonin2A (5-HT2A) Receptors in Epilepsy
Vincenzo Crunelli, Marcello Venzi, Philippe Deurwaerdère, Giuseppe Giovanni

17. 5-HT2A Receptors and BDNF Regulation: Implications for Psychopathology
Minal Jaggar, Vidita A. Vaidya

Avainsanat: Biomedicine, Neurosciences, Neurobiology