Cellular and Molecular Approaches to Regeneration and Repair

Part I. Stem Cells

1. Stroke: Cytoprotection, Repair and Regeneration—The Continuum of Patient Care
Paul A. Lapchak

2. Interdisciplinary Advances Towards Understanding and Enhancing the Therapeutic Potential of Stem Cell-Based Therapies for Ischaemic Stroke
Pascal Gervois, Yörg Dillen, Tim Vangansewinkel, Petra Hilkens, Ronald B. Driesen, Greet Merckx, Melissa Lo Monaco, Jessica Ratajczak, Annelies Bronckaers, Ivo Lambrichts, Esther Wolfs

3. Stem Cell Transplants in the Aged Stroke Brain: Microenvironment Factors
Aurel Popa-Wagner, Mario Napoli

4. Modulating Endogenous Adult Neural Stem Cells to Improve Regeneration in Stroke Brain
Fucheng Luo, Yu Luo

5. Mobilization of Endogenous Neural Stem Cells to Promote Regeneration After Stroke
Monika Rabenstein, Maria Adele Rueger

6. Transcriptional and Genomic Advances on the Pathophysiology of Stem Cell Repairment After Intracerebral Hemorrhage
Sheng Zhang, Yongjie Zhou, Yujie Chen

7. Modulation of Post-Stroke Plasticity and Regeneration by Stem Cell Therapy and Exogenic Factors
Lukas Andereggen, Raluca Reitmeir, Stefano Di Santo, Raphael Guzman, Hans R. Widmer, Serge Marbacher, Robert H. Andres

8. Stem Cell-Paved Biobridge: A Merger of Exogenous and Endogenous Stem Cells Toward Regenerative Medicine in Stroke
Hung Nguyen, M. Grant Liska, Marci G. Crowley, Cesario V. Borlongan

9. Bone-Marrow-Derived Cell Therapies in Stroke: Immunomodulatory Effects
Laith Maali, David C. Hess

10. The Combination of Stem Cell Factor (SCF) and Granulocyte-Colony Stimulating Factor (G-CSF) in Repairing the Brain Post-acute Stroke
Li-Ru Zhao, Suning Ping, Fei Hao

11. Mesenchymal Stromal Cell Therapy of Stroke
Yi Shen, Poornima Venkat, Michael Chopp, Jieli Chen

12. Combination Treatment of Mesenchymal Stem Cells (MSCs) and Angelica sinensis’ Active Ingredients for Ischemic Stroke
Qian Zhang, Yonghua Zhao

13. Gene Therapy for Cognitive Recovering After Ischemic Stroke
Johanna Gutierrez-Vargas, Rafael Posada-Duque, Gloria Patricia Cardona-Gómez

14. SB623 Preclinical and Clinical Trial Experience
Eric S. Sussman, Gary K. Steinberg

15. Preparing for Future Stem Cell Clinical Trials
Keith W. Muir

Part II. Exosomes-miRNA

16. Extra-Cellular Vesicles: A Promising Approach for Translating Cell-Based Therapy
Benjamin Buller, Michael Chopp, Zheng Gang Zhang

17. Exosome and MiRNA in Stroke
Ji Bihl, Jinju Wang, Xiaotang Ma, Yi Yang, Bin Zhao, Yanfang Chen

Part III. Neuronal Environment, Plasticity and Repair Mechanisms

18. Integrating Molecular, Cellular, and Systems Approaches to Repairing the Brain After Stroke
Max O. Krucoff, Stephen C. Harward, Shervin Rahimpour, Keith Dombrowski, Erik F. Hauck, Shivanand P. Lad, Dennis A. Turner

19. Neural Network Regeneration After Stroke
Norihito Shimamura, Takeshi Katagai, Masato Naraoka, Hiroki Ohkuma

20. The Role of Matricellular Proteins in Experimental Subarachnoid Hemorrhage-Induced Early Brain Injury
Lei Liu, Hidenori Suzuki

21. Chemokines and Proteolysis: Implications for Stem Cell Dynamics in Ischemic Stroke
Umadevi V. Wesley, Robert J. Dempsey

22. The NLRP3 Inflammasome: A Possible Therapeutic Target for Treatment of Stroke
Tauheed Ishrat, Sanaz Nasoohi

23. Microglial Function in Intracerebral Hemorrhage Injury and Recovery
A-Hyun Cho, Neethu Michael, David H. Cribbs, Mark J. Fisher

24. The Role of T Cells in Post-stroke Regeneration
Julia V. Cramer, Arthur Liesz

25. The Inflammatory Response and Its Effect on Rehabilitation-Induced Repair Processes After Stroke
Ali Alawieh, Farris Langley, Stephen Tomlinson

26. Complement C3a: Shaping the Plasticity of the Post-stroke Brain
Anna Stokowska, Marcela Pekna

Avainsanat: Biomedicine, Neurosciences, Neurology