Sickle Cell Disease and Hematopoietic Stem Cell Transplantation

Part I. Sickle Cell Disease

1. Clinical Manifestations of Sickle Cell Disease Across the Lifespan
Lydia H. Pecker, Jane Little

2. Pathobiology of Sickle Cell Disease Vaso-occlusion and Targeted Therapies
Kerry A. Morrone, Jennifer Davila, W. Beau Mitchell, Deepa Manwani

3. Current Non-HSCT Treatments for SCD
Claire L. Anderson, Deepika S. Darbari

4. Risk-Based Therapies for Sickle Cell Disease
Emily Riehm Meier

5. Transfusion Support of the Patient with Sickle Cell Disease Undergoing Transplantation
Jeanne E. Hendrickson, Ross M. Fasano

6. Neurological Manifestations of Sickle Cell Disease and Their Impact on Allogeneic Hematopoietic Stem Cell Transplantation
Jessica L. Carpenter, Monica L. Hulbert

Part II. Hematopoietic Stem Cell Transplantation

7. Overview of Hematopoietic Stem Cell Transplantation for Nonmalignant Diseases
Karen L. Zimowski, Shanmuganathan Chandrakasan

8. Unique Challenges of Hematopoietic Stem Cell Transplant for Sickle Cell Disease
Pooja Khandelwal, Michael Grimley

9. The Ethics of Hematopoietic Stem Cell Transplantation for Sickle Cell Disease
Robert Sheppard Nickel, Naynesh Kamani

10. Psychosocial Care and Education of Children with Sickle Cell Disease Undergoing Hematopoietic Stem Cell Transplant and Their Families
Steven J. Hardy, Jasmine Holt, Amanda L. Thompson

11. Long-Term Effects of Hematopoietic Stem Cell Transplantation for Sickle Cell Disease
Karim T. Sadak, Angela R. Smith, Monica Bhatia

12. Matched Sibling Donor Hematopoietic Stem Cell Transplantation for Sickle Cell Disease
Gregory M. T. Guilcher, John T. Horan

13. Unrelated Donor Hematopoietic Stem Cell Transplantation for Sickle Cell Disease
Alexander Ngwube, Shalini Shenoy

14. Haploidentical Hematopoietic Cell Transplantation for Sickle Cell Disease
Elizabeth O. Stenger, Allistair Abraham

15. Gene Therapy: The Path Toward Becoming a Realistic Cure for Sickle Cell Disease
Alexis Leonard, Allistair Abraham

Avainsanat: Medicine & Public Health, Hematology