Molecular Basis for Mitochondrial Signaling

Part I. Mitochondrial Calcium Signaling

1. Mitochondrial Ca2+ Handling and Behind: The Importance of Being in Contact with Other Organelles
Riccardo Filadi, Pierre Theurey, Alice Rossi, Chiara Fedeli, Paola Pizzo

2. Molecular Players of Mitochondrial Calcium Signaling: Similarities and Different Aspects in Various Organisms
Vanessa Checchetto, Diego Stefani, Anna Raffaello, Rosario Rizzuto, Ildiko Szabo

Part II. The Mitochondrial Permeability Transition Pore: Structure and Function

3. The Mitochondrial Permeability Transition Pore: Molecular Structure and Function in Health and Disease
Elizabeth A. Jonas, George A. Porter, Gisela Beutner, Nelli Mnatsakanyan, Han-A. Park, Nikita Mehta, Rongmin Chen, Kambiz N. Alavian

4. Mitochondrial Calcium Uptake in Activation of the Permeability Transition Pore and Cell Death
Maria E. Solesio, Evgeny V. Pavlov

Part III. Mitochondrial Outer Membrane Transport Systems: Structure, Function, and Physiological Implications

5. Voltage-Dependent Anion Channels and Tubulin: Bioenergetic Controllers in Cancer Cells
Eduardo N. Maldonado, David N. DeHart, John J. Lemasters

6. An Assessment of How VDAC Structures Have Impacted Our Understanding of Their Function
Lucie Bergdoll, Michael Grabe, Jeff Abramson

7. Plant VDAC Permeability: Molecular Basis and Role in Oxidative Stress
Fabrice Homblé, Hana Kmita, Hayet Saidani, Marc Léonetti

8. Lipids in Regulation of the Mitochondrial Outer Membrane Permeability, Bioenergetics, and Metabolism
Tatiana K. Rostovtseva, David P. Hoogerheide, Amandine Rovini, Sergey M. Bezrukov

9. The Mitochondrial Outer Membrane Potential as an Electrical Feedback Control of Cell Energy Metabolism
Victor V. Lemeshko

Part IV. Mitochondria and Cellular Signaling Network

10. New Insights on the Regulation of Programmed Cell Death by Bcl-2 Family Proteins at the Mitochondria: Physiological and Pathophysiological Implications
Laurent Dejean, Stéphen Manon

11. The 18 kDa Translocator Protein (TSPO): Cholesterol Trafficking and the Biology of a Prognostic and Therapeutic Mitochondrial Target
Michele Frison, Anna Katherina Mallach, Emma Kennedy, Michelangelo Campanella

12. Protein Import Channels in the Crossroads of Mitochondrial Function
Ma Su Su Aung, Ruth Hartke, Stephen Madamba, Oygul Mirzalieva, Pablo M. Peixoto

13. Substrate Selection and Its Impact on Mitochondrial Respiration and Redox
Sonia Cortassa, Steven J. Sollott, Miguel A. Aon

Avainsanat: Physics, Biological and Medical Physics, Biophysics, Cell Cycle Analysis, Apoptosis