Diffuse Low-Grade Gliomas in Adults

1. Introduction: From the Inhibition of Dogmas to the Concept of Personalized Management in Patients with Diffuse Low-Grade Gliomas
Hugues Duffau

Part I. Epidemiology and Classification

2. Epidemiology of Diffuse Low Grade Gliomas
Luc Bauchet

3. Molecular Epidemiology of Diffuse Low-Grade Glioma
Daniel I. Jacobs, Elizabeth B. Claus, Margaret R. Wrensch

4. Molecular-Genetic Classification of Gliomas and Its Practical Application to Diagnostic Neuropathology
José E. Velázquez Vega, Daniel J. Brat

5. Towards an Intermediate Grade in Glioma Classification
Valérie Rigau

Part II. Fundamental Science

6. Pathogenesis of Diffuse Low-Grade Gliomas
Courtney Pendleton, Kazuya Motomura, Atsushi Natsume

7. Dissemination of Diffuse Low-Grade Gliomas: Tools and Molecular Insights
Nicolas Leventoux, Zahra Hassani, Jean-Philippe Hugnot

8. The Genomics of Diffuse Low-Grade Gliomas
Maleeha Ahmad, Robert J. Weil, Nicholas F. Marko

9. Diffuse Low-Grade Glioma Associated Stem Cells
Federica Caponnetto, Antonio Paolo Beltrami, Tamara Ius, Miran Skrap, Daniela Cesselli

10. Molecular Imaging of Diffuse Low Grade Glioma
Whitney B. Pope, Kevin Spitler

Part III. Clinical Aspects and Diagnostic Imaging

11. Clinical Presentation in Diffuse Low-Grade Gliomas
Anja Smits, Asgeir S. Jakola

12. Epilepsy and Diffuse Low-Grade Gliomas
Johan Pallud

13. Quality of Life in Patients with Diffuse Low-Grade Glioma
Martin Klein

14. Magnetic Resonance Oncometabolic Imaging in DLGG Beyond the Image
Rémy Guillevin, Guillaume Herpe, Carole Guillevin

15. Positron-Emission-Tomography in Diffuse Low-Grade Gliomas
Karl-Josef Langen, Marion Rapp, Michael Sabel, Norbert Galldiks

16. Dynamics of DLGG and Clinical Implications
Emmanuel Mandonnet

17. Natural History and Spontaneous Prognostic Factors
Roberta Rudà, Alessia Pellerino, Riccardo Soffietti

Part IV. Functional Assessment and Interaction with the Brain

18. Language, Cognitive and Emotional Evaluations
Sylvie Moritz-Gasser, Guillaume Herbet

19. Task-Based and Resting-State Functional MRI in DLGG
Alexandre Krainik, Jérôme Cochereau

20. Diffusion Magnetic Resonance Imaging in Diffuse Low-Grade Gliomas
Sonia Pujol

21. Magnetoencephalography, Functional Connectivity and Neural Network Topology in Diffuse Low-Grade Gliomas
Linda Douw, Jan J. Heimans, Jaap C. Reijneveld

22. Interactions Between Diffuse Low-Grade Glioma (DLGG), Brain Connectome and Neuroplasticity
Hugues Duffau

Part V. New Insights into the Therapeutic Strategies for DLGG

23. Surgery for Diffuse Low-Grade Gliomas (DLGG) Oncological Outcomes
Hugues Duffau

24. Surgery for Diffuse Low-Grade Gliomas (DLGG) Functional Ouctomes
Hugues Duffau

25. Chemotherapy for Diffuse Low Grade Gliomas
Luc Taillandier, Marie Blonski

26. Radiation Therapy in the Treatment of Low Grade Gliomas
Hunter Boggs, Minesh Mehta

27. Functional Rehabilitation in Patients with DLGG
Guillaume Herbet, Sylvie Moritz-Gasser

28. New Individualized and Dynamic Therapeutic Strategies in DLGG
Hugues Duffau, Luc Taillandier

Part VI. Prospects

29. Emerging Therapies for Diffuse Low Grade Glioma
James Wright, Andrew Edward Sloan

30. Pregnancy and Diffuse Low-Grade Gliomas
Sophie Peeters, Johan Pallud

31. Biomathematical Modeling of DLGG
Emmanuel Mandonnet

32. Resection Probability Maps of Glioma
Philip C. Witt Hamer, Emmanuel Mandonnet, Hugues Duffau

33. The Concept of Onco-Functional Balance in the Management of DLGG
Emmanuel Mandonnet, Hugues Duffau

34. The Origins of Diffuse Low-Grade Gliomas
Amélie Darlix, Catherine Gozé, Valérie Rigau, Luc Bauchet, Luc Taillandier, Hugues Duffau

35. From Management of Incidental DLGG to Screening of Silent DLGG
Emmanuel Mandonnet, Luc Taillandier, Hugues Duffau

Avainsanat: Medicine & Public Health, Oncology, Neurology, Neuroradiology