Melanoma Development

1. Clinicopathologic Overview of Melanoma
Anja Bosserhoff, Luigi Strizzi

2. Revisiting Epidermal Melanocytes: Regulation of Their Survival, Proliferation, and Function in Human Skin
Zalfa A. Abdel-Malek, Viki B. Swope, Arup Indra

3. Melanoma Epidemiology
Marianne Berwick

4. Melanoma Genetics and Genomics
Allen Ho, Göran Jönsson, Hensin Tsao

5. Transcriptional Regulation in Melanoma
Satoru Yokoyama, David E. Fisher

6. MiRNAs in Malignant Melanoma
Maria Mione, Janika Liebig, Leonel Munoz, Anja Bosserhoff

7. Altered Signal Transduction Pathways in Melanoma
Yann Cheli, Eric Lau, Ze’ev A. Ronai

8. Proteases in Melanoma
Paola Zigrino, Cornelia Mauch

9. Cell–Cell Contacts in Melanoma and the Tumor Microenvironment
Silke Kuphal, Nikolas K. Haass

10. Regulation of Apoptosis in Melanoma Cells: Critical Targets for Therapeutic Strategies
Jürgen Eberle, Lothar F. Fecker

11. Senescence
Helen Rizos, Sebastian Haferkamp, Lyndee L. Scurr

12. Melanoma Stem Cells
Tobias F. I. Schatton, Markus H. Frank

13. The Birth of Malignancy: Embryogenesis and Melanoma
Alec Gramann, William Tyler Frantz, Craig J. Ceol

14. Tumor Microenvironment for Melanoma Cells
Lawrence W. Wu, Meenhard Herlyn, Gao Zhang

15. Melanoma Model Systems
Birgit Schittek, Miriam Jel, Thomas Tüting

16. New Approaches to Signaling
Ryan J. Sullivan, Keith T. Flaherty

17. Immune Checkpoint Inhibitors in Melanoma Define a New Era in Immunotherapy Aiming for Cure
Alexander M. M. Eggermont, Dirk Schadendorf, Caroline Robert

Avainsanat: Biomedicine, Cancer Research