Pruritus

Part I. Neurophysiology

1. Neural Processing of Itch
Tasuku Akiyama, E. Carstens

2. Pruriceptors
Ethan A. Lerner

3. Central Representation of Itch
Hideki Mochizuki, Gil Yosipovitch

4. Interaction of Pruritus and Pain
Martin Schmelz

5. Modulation of Pruritus: Peripheral and Central Sensitization
Martin Schmelz

6. In Vitro Models of Itch
Nicolas Lebonvallet, Laurent Misery

7. Measurement of Sensory Function in Chronic Pruritus
Esther Pogatzki-Zahn, Manuel P. Pereira, Martin Tegenthoff

Part II. Clinics

8. Pruritus, Pain and Other Abnormal Skin Sensations
Laurent Misery

9. Epidemiology
Elke Weisshaar, Florence Dalgard

10. Classification
Claudia Zeidler, Sonja Ständer

11. Examination of Patients
Elke Weisshaar, Markus Streit

12. Measurement of Itch: Patient-Reported Outcomes
Sonja Ständer

13. Measurement of Itch: Actigraphy
Toshiya Ebata

14. Placebo and Nocebo Effects on Itch: Methodological and Clinical Implications
Andrea W. M. Evers, Kaya J. Peerdeman, Danielle J. P. Bartels, Antoinette I. M. Laarhoven

15. Patient Needs and Treatment Goals in Clinical Care of Chronic Pruritus
Sabine Steinke, Christine Blome, Matthias Augustin

16. Sex- and Gender-Specific Differences in Chronic Pruritus
Astrid Stumpf, Bettina Pfleiderer

17. Clinical Presentation of Itch
Asit Mittal, Sonja Ständer

18. Sensitive Skin
Laurent Misery

19. Atopic Dermatitis
Mitsutoshi Tominaga, Kenji Takamori

20. Allergic and Irritant Contact Dermatitis
Eduardo Rozas-Muñoz, Esther Serra-Baldrich

21. Urticaria
Tabi A. Leslie, Ulrike Raap

22. Mastocytosis
Undine Lippert

23. Cutaneous Drug Reactions and Drug-Induced Pruritus
Jacek C. Szepietowski, Adam Reich, Franz Legat

24. Psoriasis
Adam Reich, Jacek C. Szepietowski

25. Autoimmune Diseases
Yozo Ishiuji, Alan B. Fleischer

26. Itch, Infections and Infestations
Gentiane Monsel, Eric Caumes

27. Cutaneous Lymphoma
Hiroyuki Murota, Ichiro Katayama

28. Neuropathic Pruritus Secondary to Brain and Spinal Cord Tumors
Laurent Misery

29. Notalgia Paresthetica
Ekin Şavk

30. Brachioradial Pruritus
Astrid Stumpf, Claudia Zeidler, Sonja Ständer

31. Other Forms of Neuropathic Pruritus
Astrid Stumpf, Claudia Zeidler, Sonja Ständer

32. Small-Fibre Neuropathies
Emilie Brenaut, Laurent Misery

33. Chronic Kidney Diseases
Thomas Mettang

34. Hepatobiliary Diseases
Wiebke Pirschel, Andreas E. Kremer

35. Endocrine Diseases
Andreas E. Kremer, Elke Weisshaar

36. Pruritus in Hematological Diseases (Including Aquagenic Pruritus)
Christelle Gall-Ianotto, Laurent Misery

37. Cancers
Elke Weisshaar

38. The Burden of Itch
Florence Dalgard, Jörg Kupfer, Laurent Misery

39. Psychological Approach
Laurent Misery, Gudrun Schneider

40. Psychosomatic Aspects and Psychiatric Conditions
Gudrun Schneider

41. Psychogenic Pruritus
Laurent Misery

42. Pruritus in Children
Claire Abasq-Thomas, Matthieu Gréco, Laurent Misery

43. Pruritus Vulvae
Micheline Moyal-Barracco

Part III. Treatment

44. General Principles and Guidelines
Sonja A. Grundmann, Sonja Ständer

45. Capsaicin
Laurent Misery

46. Topical Steroids and Immunomodulators
Laurent Misery

47. Menthol, Camphor and Other Topical Treatments
Laurent Misery

48. Antihistamines
Caroline Gaudy-Marqueste

49. Anticonvulsants
Simone Garcovich

50. Opioid Receptor Antagonists or Agonists
Laurent Misery

51. Antidepressants
Elke Weisshaar

52. Immunosuppressants
Carolyn Stull, Michael Joseph Lavery, Gil Yosipovitch

53. NK-1 Antagonists
Sonja Ständer

54. Psychological Intervention
Laurent Misery, Gudrun Schneider

55. Ultraviolet Phototherapy of Pruritus
Joanna Wallengren

56. Acupuncture
Laurent Misery

57. Future Perspectives: New and Modern Therapies
Sonja Ständer, Laurent Misery

Avainsanat: Medicine & Public Health, Dermatology, Infectious Diseases, Epidemiology, Primary Care Medicine, General Practice / Family Medicine