Protein Targeting Compounds

Part I. Methods of Structure Prediction

1. In Silico Prediction of Target-Inhibitor Interaction
Joachim Reichelt

Part II. Antibodies

2. Antibodies and Selection of Monoclonal Antibodies
Katja Hanack, Katrin Messerschmidt, Martin Listek

3. Selection of Recombinant Human Antibodies
Florian Tomszak, Susanne Weber, Jonas Zantow, Thomas Schirrmann, Michael Hust, André Frenzel

4. Generation of Recombinant Antibodies Against Toxins and Viruses by Phage Display for Diagnostics and Therapy
Tobias Unkauf, Sebastian Miethe, Viola Fühner, Thomas Schirrmann, André Frenzel, Michael Hust

5. Recent Advances with ER Targeted Intrabodies
Andrea L. J. Marschall, Stefan Dübel, Thomas Böldicke

6. Therapeutic Antibodies in Cancer Therapy
Martin Gasser, Ana Maria Waaga-Gasser

7. Synthetic Cystine-Knot Miniproteins – Valuable Scaffolds for Polypeptide Engineering
Olga Avrutina

Part III. Peptides, Small Molecules and Aptamers

8. Peptides and Peptide Analogs to Inhibit Protein-Protein Interactions
Dorothea Helmer, Katja Schmitz

9. Allosteric Modulators of the Class A G Protein Coupled Receptors
Nuska Tschammer

10. Phosphatases: Their Roles in Cancer and Their Chemical Modulators
Miriam Fontanillo, Maja Köhn

11. Selection and Application of Aptamers and Intramers
Meltem Avci-Adali

Part IV. Angiogenesis Inhibitors

12. Inhibitors of Angiogenesis
H. Büning, U. T. Hacker

Avainsanat: Biomedicine, Immunology