Ocular Transporters In Ophthalmic Diseases And Drug Delivery

I.Transport in the Anterior Segment

1. Aquaporins and Water Transport in the Cornea
Alan S. Verkman

2. Roles of Corneal Epithelial Ion Transport Mechanisms in Mediating Responses to Cytokines and Osmotic Stress
Peter S. Reinach, José E. Capó-Aponte, Stefan Mergler, Kathryn S. Pokorny

3. Vitamin C Transport, Delivery, and Function in the Anterior Segment of the Eye
Ram Kannan, Hovhannes J. Gukasyan

II.Transporters of the Ciliary Epithelium

4. Mechanisms of Aqueous Humor Formation
Chi-wai Do, Chi-wing Kong, Chu-yan Chan, Mortimer M. Civan, Chi-ho To

III.Lens Transporters

5. Membrane Transporters
Paul J. Donaldson, Julie Lim

6. Lens Na+, K+-ATPase
Nicholas A. Delamere, Shigeo Tamiya

IV.Transport Across the Blood–Retinal Barrier

7. Pathophysiology of Pericyte-containing Retinal Microvessels
Donald G. Puro

8. Molecular Mechanisms of the Inner Blood-Retinal Barrier Transporters
Masatoshi Tomi, Ken-ichi Hosoya

V.Transport Across the Retinal Pigment Epithelium

9. Regulation of Transport in the RPE
Adnan Dibas, Thomas Yorio

10. Glucose Transporters in Retinal Pigment Epithelium Development
Lawrence J. Rizzolo

11. Ca2+ Channels in the Retinal Pigment Epithelium
Olaf Strauss

12. Taurine Transport Pathways in the Outer Retina in Relation to Aging and Disease
Ali A. Hussain, John Marshall

13. P-Glycoprotein Expression and Function in the Retinal Pigment Epithelium
Paul A. Constable, John G. Lawrenson, N. Joan Abbott

VI.Transporters in the Retina

14. The Retinal Rod NCKX1 and Cone/Ganglion Cell NCKX2 Na+/Ca2+-K+ Exchangers
Paul P. M. Schnetkamp, Yoskiyuki Shibukawa, Haider F. Altimimi, Tashi G. Kinjo, Pratikhya Pratikhya, Kyeong Jing Kang, Robert T. Szerencsei

15. Excitatory Amino Acid Transporters in the Retina
Vijay Sarthy, David Pow

16. Localization and Function of Gamma Aminobutyric Acid Transporter 1 in the Retina
Giovanni Casini

VII.Genetic Variants of Ocular Transporters

17. Biochemical Defects Associated with Genetic Mutations in the Retina-Specific ABC Transporter, ABCR, and Macular Degenerative Diseases
Esther E. Biswas-Fiss

18. Glutamate Transporters and Retinal Disease and Regulation
Nigel L. Barnett, Natalie D. Bull

19. Glutamate Transport in Retinal Glial Cells during Diabetes
Erica L. Fletcher, Michelle M. Ward

VII.Ocular Drug Delivery

20. The Emerging Significance of Drug Transporters and Metabolizing Enzymes to Ophthalmic Drug Design
Mayssa Attar, Jie Shen

21. Barriers in Ocular Drug Delivery
Sriram Gunda, Sudharshan Hariharan, Nanda Mandava, Ashim K. Mitra

22. Ophthalmic Applications of Nanotechnology
Swita Raghava, Gaurav Goel, Uday B. Kompella

23. Vitamin C Transporters in the Retina
Vadivel Ganapathy, Sudha Ananth, Sylvia B. Smith, Pamela M. Martin

24. The Plasma Membrane Transporters and Channels of Corneal Endothelium
Jorge Fischbarg

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Avainsanat: MEDICAL / Public Health MED078000