Effect of Spaceflight and Spaceflight Analogue Culture on Human and Microbial Cells

Part I. The Principles and Translational Impact of Space Life Sciences Research

1. Overview and Translational Impact of Space Cell Biology Research
Neal R. Pellis, Alexander Chouker, B. Yic, Svantje Tauber, Oliver Ullrich, A. Sundaresan

2. Principles of Analogue and True Microgravity Bioreactors to Tissue Engineering
David A. Wolf, Stanley J. Kleis

3. Immune Dysfunction in Spaceflight: An Integrative View
Buqing Yi, Brian Crucian, Svantje Tauber, Oliver Ullrich, Alexander Choukèr

Part II. Human Cellular Investigations

4. Biomedical Advances in Three Dimensions: An Overview of Human Cellular Studies in Space and Spaceflight Analogues
Cheryl A. Nickerson, C. Mark Ott

5. Outpacing Infectious Disease: Mimicking the Host-Pathogen Microenvironment in Three-Dimensions
Aurélie Crabbé, Jennifer Barrila, C. Mark Ott, Cheryl A. Nickerson

6. Use of In Vitro Cell Culture Models to Understand the Cellular and Molecular Basis of Immune Dysfunction During Spaceflight
Svantje Tauber, Buqing Yi, Alexander Choukèr, Oliver Ullrich

7. Using a Spaceflight Three-Dimensional Microenvironment to Probe Cancer–Stromal Interactions
Ruoxiang Wang, Gina Chia-Yi Chu, Haiyen E. Zhau, Leland W. K. Chung

8. Skeletal Muscle Culture Under Spaceflight Conditions
Mark S. F. Clarke

9. Microgravity and Microgravity Analogue Studies of Cartilage and Cardiac Tissue Engineering
Kacey Ronaldson, Gordana Vunjak-Novakovic

Part III. Microbial Investigations

10. Microbial Investigations: Overview
Duane L. Pierson, C. Mark Ott

11. Using Spaceflight and Spaceflight Analogue Culture for Novel Mechanistic Insight into Salmonella Pathogenesis
Jennifer Barrila, James W. Wilson, Anjali Soni, Jiseon Yang, C. Mark Ott, Cheryl A. Nickerson

12. Response of Pseudomonas aeruginosa to Spaceflight and Spaceflight Analogue Culture: Implications for Astronaut Health and the Clinic
Aurélie Crabbé, Maria A. Ledesma, C. Mark Ott, Cheryl A. Nickerson

13. Cellular Response of Escherichia coli to Microgravity and Microgravity Analogue Culture
Rachna Singh, A. C. Matin

14. Spaceflight and Spaceflight Analogue Induced Responses in Gram Positive Bacteria
Sarah L. Castro, David W. Niesel, Jennifer Barrila, C. Mark Ott

Avainsanat: Biomedicine, Immunology, Medical Microbiology, Infectious Diseases, Extraterrestrial Physics, Space Sciences