Diabetic Cardiomyopathy

Part I. Metabolic Derangements in Diabetic Cardiomyopathy

1. Metabolic Alterations in Diabetic Cardiomyopathy
Kimberly-Ann M. Bordun, Davinder S. Jassal, Naranjan S. Dhalla

2. Metabolic and Contractile Remodelling in the Diabetic Heart: An Evolutionary Perspective
Vijay Sharma, John H. McNeill

3. Induction of Metabolic Syndrome by Excess Fructose Consumption
Weng-Yew Wong, Lindsay Brown

4. Substrate Metabolism in the Diabetic Heart
Arzu Onay-Besikci

5. Effects of Diabetes-Induced Hyperglycemia in the Heart: Biochemical and Structural Alterations
Tahreem Iqbal, Philip J. Welsby, Frank C. Howarth, Keshore Bidasee, Ernest Adeghate, Jaipaul Singh

6. Hyperglycemia, Oxidative Stress, and Vascular Complications: Role of Epigenetic Mechanisms
Estelle R. Simo Cheyou, Ashok K. Srivastava

7. A Critical Balance Between Oxidative Stress and Antioxidant Defense in Cardiovascular System Under Hyperglycemia: A Summary of Experimental Studies
Murat Ayaz, Belma Turan

8. Aldose Reductase and Diabetic Cardiovascular Disease
Mariane Abdillahi, Ravichandran Ramasamy

9. Sex Differences and Diabetes Mellitus in Cardiovascular Function
Semir Ozdemir, Nazmi Yaras, Belma Turan

Part II. Cellular Mechanisms of Diabetic Cardiomyopathy

10. MicroRNomics of Diabetic Cardiomyopathy
Paras K. Mishra, Suresh C. Tyagi

11. Cellular Mechanism Underlying the Misfunction of Cardiac Ionic Channels in Diabetes
Mónica Gallego, Oscar Casis

12. Role of PPAR-δ in Diabetic Cardiomyopathy
Ying-Xiao Li, Kai-Chun Cheng, Juei-Tang Cheng

13. The Role of Inflammation in Type 2 Diabetes-Driven Atherosclerosis
Jennifer E. Enns, Carla G. Taylor, Peter Zahradka

14. Cardiovascular Autonomic Neuropathy in Diabetes
Takahide Arai, Masaki Ieda, Keiichi Fukuda

15. Liver and Fat in Type 2 Diabetes: New Insights and Clinical Relevance
Mukesh Nandave, Anup Ramdhave, Ramesh K. Goyal

16. Roles of PKC Isoforms in Development of Diabetes-Induced Cardiovascular Complications
Isil Ozakca, A. Tanju Ozcelikay

17. Calcium-Handling Proteins in Diabetic Cardiomyopathy
Vijayan Elimban, Adriana Frota P. Pinto, Naranjan S. Dhalla

18. Abnormalities in ATP Production and Utilization in Diabetic Cardiomyopathy
Naranjan S. Dhalla, Arthur H. Cunha-Volpato, Yan-Jun Xu

Part III. Therapeutic Aspects of Diabetic Cardiomyopathy

19. The Next Generation of Diagnostic Biomarkers for Type 2 Diabetes
Samarjit Das, Tengku Ain Kamalden

20. PDE-5 Inhibitors in Protection of Diabetic Heart
Saisudha Koka, Rakesh C. Kukreja

21. Restoration of Angiogenesis: A Promising Therapeutic Strategy in Diabetic Cardiomyopathy
Veeranjaneyulu Addepalli, Dipti Gatne

22. The Angiotensin-Converting Enzyme 2/Angiotensin-(1-7)/Mas Receptor Axis: A Potential Target for Treating Diabetic Cardiovascular Disease
Ibrahim F. Benter, Mariam H. M. Yousif, Jasbir S. Juggi, Saghir Akhtar

23. Targeting Matrix Metalloproteinase 2 and 9 for Treatment of Cardiovascular Dysfunction of Diabetes
Lokesh Kumar Bhatt, Veeranjaneyulu Addepalli

24. Nutraceutical Approaches in the Management of Cardiovascular Dysfunctions Associated with Diabetes Mellitus
Saloni Daftardar, Ginpreet Kaur, Veeranjaneyulu Addepalli

25. Nutritional Management of Cardiovascular Complications Caused by Diabetes
Adriana Adameova, Paramjit S. Tappia, Yan-Jun Xu, Naranjan S. Dhalla

Avainsanat: Life Sciences, Proteomics, Diabetes, Cardiology, Human Physiology, Membrane Biology, Medical Biochemistry