Pharmaco-Imaging in Drug and Biologics Development

1. Imaging Platforms and Drug Development: An Introduction
Brian R. Moyer

2. Imaging in Drug Development: Animal Models, Handling and Physiological Constraints
David B. Stout

3. Considerations for Preclinical Laboratory Animal Imaging Center Design, Setup, and Management Suitable for Biomedical Investigation for Drug Discovery
Brenda A. Klaunberg, H. Douglas Morris

4. Pharmaco-Imaging in Translational Science and Research
Immanuel Freedman

5. The Role of Pharmacokinetics and Allometrics in Imaging: Practical Issues and Considerations
Brian R. Moyer

6. Quantitative Imaging Using Autoradiographic Techniques
Eric G. Solon, Brian R. Moyer

7. Preclinical Imaging in Oncology: Considerations and Recommendations for the Imaging Scientist
Daniel P. Bradley, Tim Wyant

8. Use of Radiolabelled Leukocytes for Drug Evaluation in Man
Chrystalla Loutsios, Neda Farahi, Charlotte Summers, Prina Ruparelia, Jessica White, Jonathan Potts, Chandra K. Solanki, Kishor Solanki, Sarah Heard, Daniel Gillett, Kottekkattu K. Balan, Alison M. Condliffe, A. Michael Peters, Edwin R. Chilvers

9. Application of Bioluminescence Imaging (BLI) to the Study of the Animal Models of Human Infectious Diseases
Hana Golding, Marina Zaitseva

10. Preclinical Imaging in BSL-3 and BSL-4 Environments: Imaging Pathophysiology of Highly Pathogenic Infectious Diseases
Lauren Keith, Svetlana Chefer, Laura Bollinger, Jeffrey Solomon, Srikanth Yellayi, Jurgen Seidel, David Thomasson, Peter Jahrling

11. Magnetic Resonance as a Tool for Pharmaco-Imaging
Brian R. Moyer, Tom C.-C. Hu, Simon Williams, H. Douglas Morris

12. Technologies and Principles of Mass Spectral Imaging
Kevin A. Douglass, Demian R. Ifa, Andre R. Venter

13. Regulatory Considerations Involved in Imaging
Brian R. Moyer, Narayan P. S. Cheruvu, Tom C.-C. Hu

Avainsanat: Biomedicine, Biomedicine general, Pharmaceutical Sciences/Technology