War in the Body

1. Introduction
W. David Wick, Otto O. Yang

Part I. The Biology, Modeling, and Predictions

2. The HIV Infection Model
W. David Wick, Otto O. Yang

3. The CTL Model
W. David Wick, Otto O. Yang

4. Simulating an HIV Infection In Vivo

W. David Wick, Otto O. Yang

5. The Escape Formula
W. David Wick, Otto O. Yang

6. Early and Late Escapes
W. David Wick, Otto O. Yang

7. Understanding Escape
W. David Wick, Otto O. Yang

8. More Topics About Escape from Immune Control
W. David Wick, Otto O. Yang

9. HIV’s Cloaking Device: The Fascinating Story of Nef
W. David Wick, Otto O. Yang

10. Retroviral Sex and Escape
W. David Wick, Otto O. Yang

11. The N

e
Business, Again, and a Proposed Experiment
W. David Wick, Otto O. Yang

12. Can a T-Cell Vaccine Block Escape?
W. David Wick, Otto O. Yang

13. The STEP Trial, Monkey Trials, and the Future of T-Cell Vaccines
W. David Wick, Otto O. Yang

14. Afterword: The RV144 Trial and the Current Status of HIV Vaccine Research
W. David Wick, Otto O. Yang

Part II. The Mathematics

15. Short Tutorial on Dynamical Models
W. David Wick, Otto O. Yang

16. Deterministic Modeling: A Cautionary Example
W. David Wick, Otto O. Yang

17. The Infection Model Defined
W. David Wick, Otto O. Yang

18. The CTL Model Defined
W. David Wick, Otto O. Yang

19. On Simulation Techniques
W. David Wick, Otto O. Yang

20. Derivation of the Escape Formula
W. David Wick, Otto O. Yang

21. Statistics of the Mutant Lineage in Classical Genetics
W. David Wick, Otto O. Yang

22. Extinction Probabilities with Extra-Poisson Variation
W. David Wick, Otto O. Yang

23. Computing the Boundaries
W. David Wick, Otto O. Yang

24. Co-existence or Replacement?
W. David Wick, Otto O. Yang

25. The Nef-Deletion Threshold Formulas
W. David Wick, Otto O. Yang

26. Modeling Retroviral Sex
W. David Wick, Otto O. Yang

Avainsanat: Biomedicine, Virology, Immunology, Vaccine