Vesicle Trafficking in Cancer

1. Clathrin-Mediated Endocytosis
Alexander Sorkin, Manojkumar A. Puthenveedu

2. Intimate and Facultative? Regulation of Clathrin-Mediated Endocytosis by the Actin Cytoskeleton
Tal Hirschhorn, Marcelo Ehrlich

3. Oncogenic Signaling from the Plasma Membrane
Eli Zamir, Nachiket Vartak, Philippe I. H. Bastiaens

4. Endocytosis in the Spatial Control of Polarised Cell Functions
Giorgio Scita, Andrea Disanza, Emanuela Frittoli, Andrea Palamidessi, Sara Sigismund

5. Aberrant Vesicular Trafficking Contributes to Altered Polarity and Metabolism in Cancer
Shreya Mitra, Gordon B. Mills

6. Endocytosis and the Regulation of Cell Signaling, Cell Adhesion, and Epithelial to Mesenchymal Transition in Cancer
Crislyn D’Souza-Schorey, Guangpu Li

7. Efficient Enhancement of Signaling Capacity: Signaling Endosomes
Iwona Pilecka, Marta Miaczynska

8. Nuclear Functions and Trafficking of Receptor Tyrosine Kinases
Ying-Nai Wang, Jennifer L. Hsu, Mien-Chie Hung

9. Efficient Enhancement of Signalling Capacity: The Ubiquitin System
Daniela Hoeller, Ivan Dikic

10. Molecular Mechanism of Ubiquitin-Dependent Traffic
Elena Maspero, Hans-Peter Wollscheid, Simona Polo

11. Cbl as a Master Regulator of Receptor Tyrosine Kinase Trafficking
Ke Ma, Stephen C. Kales, Marion M. Nau, Stanley Lipkowitz

12. Regulation of Endocytic Trafficking and Signalling by Deubiquitylating Enzymes
Han Liu, Sylvie Urbé, Michael J. Clague

13. RTKs as Models for Trafficking Regulation: c-Met/HGF Receptor-c-Met Signalling in Cancer—Location Counts
Carine Joffre, Rachel Barrow, Ludovic Ménard, Stéphanie Kermorgant

14. Regulation of Epidermal Growth Factor Receptor Signaling by Endocytosis in Normal and Malignant Cells
Sergio Anastasi, Stefano Alemà, Oreste Segatto

15. Stress-Driven Endocytosis of Tyrosine-Phosphorylated EGFR Leads to Tumorigenesis: The Critical Role of Oxidative Stress
Tzipora Goldkorn, Simone Filosto, Samuel Chung

16. Internalisation, Endosomal Trafficking and Recycling of Integrins During Cell Migration and Cancer Invasion
Elena Rainero, Peter V. E. Berghe, Jim C. Norman

17. Antibody-Mediated Receptor Endocytosis: Harnessing the Cellular Machinery to Combat Cancer
Gabi Tarcic, Yosef Yarden

Avainsanat: Biomedicine, Cancer Research, Cell Biology, Biochemistry, general, Posttranslational Modification, Receptors