Formulating Poorly Water Soluble Drugs

1. Route-Specific Challenges in the Delivery of Poorly Water-Soluble Drugs
Stephanie Bosselmann, Robert O. Williams

2. Optimizing the Formulation of Poorly Water-Soluble Drugs
Kevin P. O’Donnell, Robert O. Williams

3. Solid-State Techniques for Improving Solubility
Justin R. Hughey, Robert O. Williams

4. Mechanical Particle-Size Reduction Techniques
Javier O. Morales, Alan B. Watts, Jason T. McConville

5. Solubilized Formulations
Feng Zhang, James C. DiNunzio

6. Injectable Formulations of Poorly Water-Soluble Drugs
Michael P. Boquet, Dawn R. Wagner

7. Design and Development of Self-Emulsifying Lipid Formulations for Improving Oral Bioavailability of Poorly Water-Soluble and Lipophilic Drugs
Ping Gao

8. Structured Development Approach for Amorphous Systems
Navnit Shah, Harpreet Sandhu, Duk Soon Choi, Oskar Kalb, Susanne Page, Nicole Wyttenbach

9. Melt Extrusion
James C. DiNunzio, Feng Zhang, Charlie Martin, James W. McGinity

10. Spray-Drying Technology
Dave A. Miller, Marco Gil

11. Pharmaceutical Cryogenic Technologies
Wei Yang, Donald E. Owens, Robert O. Williams

12. Precipitation Technologies for Nanoparticle Production
Jasmine M. Rowe, Keith P. Johnston

13. Emerging Technologies to Increase the Bioavailability of Poorly Water-Soluble Drugs
Justin R. Hughey, James W. McGinity

14. Scientific and Regulatory Considerations for Development and Commercialization of Poorly Water-Soluble Drugs
Zedong Dong, Hasmukh Patel

Avainsanat: Biomedicine, Pharmaceutical Sciences/Technology