Electrical Diseases of the Heart

Part I. Basic Fundamentals of Normal and Abnormal Cardiac Electrical Activity

1. Introduction to Part I: Basic Cardiac Electrophysiology – Promises Kept and Promises to Keep
Ralph Lazzara

2. Basic Physiology of Ion Channel Function
Isabelle Baró, Denis Escande, Sophie Demolombe

3. Developmental Aspects of the Electrophysiology of the Heart: Function Follows Form
Alex V. Postma, Vincent M. Christoffels, Antoon F. M. Moorman

4. Anatomic and Histopathologic Characteristics of the Conductive Tissues of the Heart
Cristina Basso, Siew Yen Ho, Stefania Rizzo, Gaetano Thiene

5. Neural Regulation of the Heart in Health and Disease
Richard L. Verrier, Alex Tan

6. Mechanisms of Cardiac Arrhythmia
Charles Antzelevitch, Alexander Burashnikov

7. Mechanisms of Action of Antiarrhythmic Drugs in Ventricular Arrhythmias
Shingo Murakami, Yoshihisa Kurachi

8. Mechanisms of Action of Antiarrhythmic Drugs in Atrial Fibrillation
Alexander Burashnikov, Charles Antzelevitch

9. Mechano-Electric Interactions and Their Role in Electrical Function of the Heart
J. Jeremy Rice, Peter Kohl

10. Pathological Roles of the Cardiac Sodium Channel Late Current (Late INa)
Sridharan Rajamani, John C. Shryock, Luiz Belardinelli

11. Sodium Ion Channelopathies
Yuka Mizusawa, Arthur A. M. Wilde, Hanno L. Tan

12. L-Type Calcium Channel Disease
Yanfei Ruan, Raffaella Bloise, Carlo Napolitano, Silvia G. Priori

13. Nerve Sprouting, Defibrillation and Calcium Waves
Mitsunori Maruyama, Shengmei Zhou, Gyo-Seung Hwang, Su-Kiat Chua, Po-Cheng Chang, Shien-Fong Lin, Lan S. Chen, Tomohiko Ai, Peng-Sheng Chen

14. K+ Channelopathies (IKs, IKr, and Ito)
Kevin J. Sampson, Robert S. Kass

15. Cardiac ATP-Sensitive Potassium Channels and Associated Channelopathies
Alexey E. Alekseev, Santiago Reyes, Satsuki Yamada, Sungjo Park, D. Kent Arrell, Garvan C. Kane, Timothy M. Olson, Andre Terzic

16. Cardiac KATP Channels in Health and Diseases
Hai Xia Zhang, Jonathan R. Silva, Colin G. Nichols

17. Ca2+ Release Channels (Ryanodine Receptors) and Arrhythmogenesis
Sameer Ather, Xander H. T. Wehrens

18. Caveolae and Arrhythmogenesis
Matteo Vatta

19. Senescence and Arrhythmogenesis
Mahek Mirza, Win-Kuang Shen, Arshad Jahangir

20. Comparisons of Substrates Responsible for Atrial Versus Ventricular Fibrillation
Philippe Comtois, Brett Burstein, Stanley Nattel

21. Single Nucleotide Polymorphisms in Health and Cardiac Disease
Eric Schulze-Bahr

22. Electrophysiological Remodeling in Heart Failure
Fadi G. Akar, Gordon F. Tomaselli

23. Ventricular Electrical Remodeling in Compensated Cardiac Hypertrophy
Vincent J. A. Bourgonje, Toon A. B. Veen, Marc A. Vos

24. Physiological and Other Biological Pacemakers
Richard B. Robinson, Peter R. Brink, Ira S. Cohen, Michael R. Rosen

25. Cardiac Memory: From Electrical Curiosity to Clinical Diagnostic and Research Tool
Alexei Shvilkin

Part II. Heritable Arrhythmogenic Channelopathies, Primary Electrical Diseases, and Sudden Cardiac Death

26. Introduction to Part Two: Celebrating the Challenge of Cardiac Arrhythmias
Jeffrey A. Towbin

27. Congenital Long QT Syndrome
David J. Tester, Peter J. Schwartz, Michael J. Ackerman

28. Brugada Syndrome: Clinical and Genetic Aspects
Paola G. Meregalli, Hanno L. Tan, Arthur A. M. Wilde

29. Brugada Syndrome: Cellular Mechanisms and Approaches to Therapy
Charles Antzelevitch, Sami Viskin

30. Early Repolarization Syndrome: Epidemiology, Genetics, and Risk Stratification
Nicolas Derval, Frédéric Sacher, Ashok Shah, Sébastien Knecht, Mélèze Hocini, Pierre Jaïs, Michel Haïssaguerre

31. Catecholaminergic Polymorphic Ventricular Tachycardia
Nian Liu, Carlo Napolitano, Silvia G. Priori

32. Andersen-Tawil and Timothy Syndromes
Martin Tristani-Firouzi, Susan P. Etheridge

33. Short QT Syndrome
Preben Bjerregaard, Ihor Gussak

34. Progressive Cardiac Conduction Disease
Jean-Jacques Schott, Flavien Charpentier, Hervé Marec

35. Genetics of Atrial Fibrillation and Standstill
Michiel Rienstra, J. Peter Tintelen, Rob A. Vermond, Bas A. Schoonderwoerd, Ans C. P. Wiesfeld, Isabelle C. Gelder

36. Idiopathic Ventricular Fibrillation
Sami Viskin, Arnon Adler, Bernard Belhassen

Avainsanat: Medicine & Public Health, Cardiology, Epidemiology, Neurology, Internal Medicine