Targeting the Wnt Pathway in Cancer

1. An Introduction to Wnt Signaling
Paul Polakis

2. Regulation of Wnt Secretion and Distribution
Xiaofang Tang, Xiaolan Fan, Xinhua Lin

3. Wnt Signaling in Stem Cells
Philipp C. Manegold, Jia-Ling Teo, Michael Kahn

4. Crosstalk of the Wnt Signaling Pathway
Michael Thompson, Kari Nejak-Bowen, Satdarshan P. S. Monga

5. Dysregulation of the Wnt Pathway in Solid Tumors
Jenifer R. Prosperi, Hue H. Luu, Kathleen H. Goss

6. WNT/β-Catenin Signaling in Leukemia
Markus Müschen

7. Use of Genetically Engineered Mouse Models in Identification and Validation of Therapeutic Targets for Colon Cancer
Masahiro Aoki, Makoto Mark Taketo

8. Targeting Wnt Signalling in Cancer
Aliaksei Holik, Alan R. Clarke

9. Inhibiting the Wnt Signaling Pathway with Small Molecules
Ho-Jin Lee, Xinxin Zhang, Jie J. Zheng

10. Targeting of Wnt Signaling Inside the Nucleus
Miki Shitashige, Tesshi Yamada

Avainsanat: Medicine & Public Health, Oncology, Pharmacology/Toxicology, Cancer Research