Cell Cycle Deregulation in Cancer

1. Escape from Cellular Quiescence
Elena Sotillo, Xavier Graña

2. Interplay Between Cyclin-Dependent Kinases and E2F-Dependent Transcription
Jun-Yuan Ji, Nicholas J. Dyson

3. Regulation of Pre-RC Assembly: A Complex Symphony Orchestrated by CDKs
A. Kathleen McClendon, Jeffry L. Dean, Erik S. Knudsen

4. Mitotic Checkpoint and Chromosome Instability in Cancer
Haomin Huang, Timothy J. Yen

5. Mitotic Catastrophe
Jeremy P.H. Chow, Randy Y.C. Poon

6. p53, ARF, and the Control of Autophagy
Robert D. Hontz, Maureen E. Murphy

7. Regulation of Self-Renewing Divisions in Normal and Leukaemia Stem Cells
Andrea Viale, Pier Giuseppe Pelicci

8. Maintenance of Telomeres in Cancer
Eros Lazzerini Denchi

9. The Senescence Secretome and Its Impact on Tumor Suppression and Cancer
Alyssa Kennedy, Peter D. Adams

10. Cell Cycle Deregulation in Pre-neoplasia: Case Study of Barrett’s Oesophagus
Pierre Lao-Sirieix, Rebecca C. Fitzgerald

11. Targeting Cyclin-Dependent Kinases for Cancer Therapy
Neil Johnson, Geoffrey I. Shapiro

Avainsanat: Biomedicine, Cancer Research, Pharmacology/Toxicology