Genome Instability in Cancer Development

1. The Multiplicity of Mutations in Human Cancers
Ranga N. Venkatesan, Lawrence A. Loeb

2. Monitoring Chromosome Rearrangements
Michael R. Speicher

3. Nucleotide Excision Repair and its Connection with Cancer and Ageing
Jaan-Olle Andressoo, Jan H.J. Hoeijmakers, Harm Waard

4. DNA Mismatch Repair and Colon Cancer
Giancarlo Marra, Josef Jiricny

5. Base Excision Repair
Lisiane B. Meira, Nicholas E. Burgis, Leona D. Samson

6. Genomic Instability in Cancer Development
Penny A. Jeggo

7. Translesion Synthesis And Errorprone Polymerases
Catherine M. Green, Alan R. Lehmann

8. The INK4A/Arf Network — Cell Cycle Checkpoint or Emergency Brake?
Ana Gutierrez Arroyo, Gordon Peters

9. DNA Replication and Genomic Instability
Wenge Zhu, Tarek Abbas, Anindya Dutta

10. The Dream of Every Chromosome: Equal Segregation for a Healthy Life of the Host
Tomohiro Matsumoto, Mitsuhiro Yanagida

11. Telomere Structural Dynamics in Genome Integrity Control and Carcinogenesis
Roger A. Greenberg, K. Lenhard Rudolph

12. Gene Amplification Mechanisms
Michelle Debatisse, Bernard Malfoy

13. DNA Methylation and Cancer-associated Genetic Instability
Melanie Ehrlich

14. Deregulation of the Centrosome Cycle and the Origin of Chromosomal Instability in Cancer
Wilma L. Lingle, Kara Lukasiewicz, Jeffrey L. Salisbury

15. Mammalian DNA Damage Response Pathway
Zhenkun Lou, Junjie Chen

16. ATM and Cellular Response to DNA Damage
Martin F. Lavin, Sergei Kozlov, Nuri Gueven, Cheng Peng, Geoff Birrell, Phillip Chen, Shaun Scott

17. Mitotic Checkpoint, Aneuploidy and Cancer
Tim J. Yen, Gary D. Kao

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Avainsanat: TECHNOLOGY & ENGINEERING / Biomedical TEC059000