Stem Cells in Birth Defects Research and Developmental Toxicology

This book contains material contributed by forward-looking scientists who work at the interface of stem cell research and applied science with the aim to improve human fetal safety and the understanding of human developmental and degenerative disorders.

• Provides important platforms and contemporary accounts of the state of stem cell research in the fields of toxicology and teratology
• Considers both in vitro uses of stem cells as platforms for teratology and also stem cellopathies, which are in vivo developmental and degenerative disorders
• Helps the pharmaceutical industry and safety and environmental authorities validate the status quo of in vitro toxicity test systems based on human pluripotent stem cells and their derivatives

Avainsanat:

Guide to Stem Cells in Birth Defects; Guide to Research on stem cells in birth defects; guide to Developmental Toxicology on stem cells in birth defects; Stem Cell Types and Basic Function; Pluripotency; Poised Chromatin of the Pluripotent Epigenome; Undirected Differentiation of Pluripotent Cells to Embryoid Bodies; Directed Differentiation of Pluripotent Cells; in vitro Uses of Pluripotent Cells; Pluripotent Cells for Toxicology; iPS Cells, Pharmacogenomics, and Predictive Teratology; Stem Cell Systems for Environmental Toxicology References; Stem Cells and Tissue Engineering Technologies for Advancing Human Teratogen Screening; in vitro Stem Cell-Based Developmental Toxicity Models; Embryonic Stem Cell Test; Reproglo Reporter Assay

, Developmental Biology, Tissue, Cell, and Genetic Engineering, Developmental Biology, Tissue, Cell, and Genetic Engineering