MALDI-TOF and Tandem MS for Clinical Microbiology

This book highlights the triumph of MALDI-TOF mass spectrometry over the past decade and provides insight into new and expanding technologies through a comprehensive range of short chapters that enable the reader to gauge their current status and how they may progress over the next decade. This book serves as a platform to consolidate current strengths of the technology and highlight new frontiers in tandem MS/MS that are likely to eventually supersede MALDI-TOF MS. Chapters discuss:
Challenges of IdentifyingMycobacterium to the Species level
Identification of Bacteroides and Other ClinicallyRelevant Anaerobes
Identification of Species inMixed Microbial Populations
Detection of ResistanceMechanisms
Proteomics as a biomarkerdiscovery and validation platform
Determination of AntimicrobialResistance using Tandem Mass Spectrometry

Avainsanat: MALDI-TOF; mass spectrometry; clinical microbiology; tandem MS/MS; MALDI-TOF Mass Spectrometry; Clinical Diagnostic Microbiology; MALDI-TOF MS; Microbial DNA Analysis;  Detection of Resistance Mechanisms; Antimicrobial Resistance; Tandem Mass Spectrometry; Top-Down Proteomics; Microbial Pathogenicity; Proteogenomics of Non-Model Microorganisms; clinical microbiologists; diagnostic technologists; biomedical scientists; identifying Mycobacterium; identification of Bacteroides; Identification of Species in Mixed Microbial Populations; Proteomics; biomarker discovery; identify microbes to the species level; microbial identification; mass spectral database; MALDI technology; strain typing;  epidemiological studies; detection of biological warfare agents; pathogen detection;  detection of antibiotic resistance; bacterial identification; identification of microorganisms; single strain typing; antibiotic resistance testing; antimycotic resistance testing; antibiotic resistance of single isolates, Clinical Microbiology (Life Sciences), Clinical Microbiology (Medical), Clinical Microbiology (Life Sciences), Clinical Microbiology (Medical)