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Goodnow, Robert A.

A Handbook for DNA-Encoded Chemistry: Theory and Applications for Exploring Chemical Space and Drug Discovery

Goodnow, Robert A. - A Handbook for DNA-Encoded Chemistry: Theory and Applications for Exploring Chemical Space and Drug Discovery, e-kirja

DRM-rajoitukset

Tulostus144 sivua ja lisä sivu kertyy joka 6. tunti, ylärajana 144 sivua
Kopioi leikepöydälle5 poimintoa

This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book:

  • Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry
  • Helps chemists generate and screen novel chemical libraries of large size and quality
  • Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry
  • Shows medicinal and pharmaceutical chemists how to efficiently broaden available “chemical space” for drug discovery
  • Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods

Avainsanat: DNA-encoded; combinatorial; drug discovery; chemical libraries; small molecules; tagging; chemistry; lead discovery; compound screening, Organic Chemistry, Biochemistry (Chemical Biology), Organic Chemistry, Biochemistry (Chemical Biology)

Tekijä(t)
Julkaisija
John Wiley and Sons, Inc.
Julkaisuvuosi
2014
Kieli
en
Painos
1
Sivumäärä
480 sivua
Kategoria
Eksaktit luonnontieteet
Tiedostomuoto
E-kirja
eISBN (ePUB)
9781118832677
Painetun ISBN
9781118487686

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