Therapeutic Targets of the TNF Superfamily

1. Overview of TNF Superfamily: A Chest Full of Potential Therapeutic Targets
Iqbal S. Grewal

2. Therapeutic Interventions Targeting CD40L (CD154) and CD40: The Opportunities and Challenges
Che-Leung Law, Iqbal S. Grewal

3. Targeting TNF for Treatment of Cancer and Autoimmunity
Gautam Sethi, Bokyung Sung, Ajaikumar B. Kunnumakkara, Bharat B. Aggarwal

4. Targeting of BAFF and APRIL for Autoimmunity and Oncology
Maureen C. Ryan, Iqbal S. Grewal

5. The Role of FasL and Fas in Health and Disease
Martin Ehrenschwender, Harald Wajant

6. OX40 (CD134) and OX40L
Michael J. Gough, Andrew D. Weinberg

7. Targeting CD70 for Human Therapeutic Use
Tamar E. Boursalian, Julie A. McEarchern, Che-Leung Law, Iqbal S. Grewal

8. 4-1BB as a Therapeutic Target for Human Disease
Seung-Woo Lee, Michael Croft

9. RANK(L) as a Key Target for Controlling Bone Loss
Andreas Leibbrandt, Josef M. Penninger

10. Targeting the LIGHT-HVEM Pathway
Carl F. Ware

11. GITR: A Modulator of Immune Response and Inflammation
Giuseppe Nocentini, Carlo Riccardi

12. Targeting CD30/CD30L in Oncology and Autoimmune and Inflammatory Diseases
Ezogelin Oflazoglu, Iqbal S. Grewal, Hanspeter Gerber

13. Tumor Necrosis Factor Receptor Superfamily Member 21: TNFR-Related Death Receptor-6, DR6
Robert Benschop, Tao Wei, Songqing Na

14. TRAIL and Other TRAIL Receptor Agonists as Novel Cancer Therapeutics
Christina Falschlehner, Tom M. Ganten, Ronald Koschny, Uta Schaefer, Henning Walczak

15. Therapeutic Potential of VEGI/TL1A in Autoimmunity and Cancer
Gautam Sethi, Bokyung Sung, Bharat B. Aggarwal

Avainsanat: Biomedicine, Biomedicine general