Targeted Therapies in Cancer

1. Causality in Medicine
Giulio Giorello

2. The Evolution of the Biomedical Paradigm in Oncology: Implications for Cancer Therapy
Gilberto Corbellini, Chiara Preti

3. Anticancer Drug Discovery and Development
Francesco Colotta

4. Beyond VEGF: Targeting Tumor Growth and Angiogenesis via Alternative Mechanisms
James Christensen, Kenna Anderes

5. Aurora Kinases and Their Inhibitors: More Than One Target and One Drug
Patrizia Carpinelli, Jürgen Moll

6. Signalling Pathways and Adhesion Molecules as Targets for Antiangiogenesis Therapy in Tumors
Gianfranco Bazzoni

7. Developing T-Cell Therapies for Cancer in an Academic Setting
Malcolm K. Brenner

8. Anticancer Cell Therapy with TRAIL-Armed CD34+ Progenitor Cells
Carmelo Carlo-Stella, Cristiana Lavazza, Antonino Carbone, Alessandro M. Gianni

9. Linking Inflammation Reactions to Cancer: Novel Targets for Therapeutic Strategies
Alberto Mantovani, Federica Marchesi, Chiara Porta, Paola Allavena, Antonio Sica

10. Clinical Development of Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitors: What Lessons Have We Learned?
Manuel Hidalgo

11. GIST As the Model of Paradigm Shift Towards Targeted Therapy of Solid Tumors: Update and Perspective on Trial Design
Jaap Verweij, Caroline Seynaeve, Stefan Sleijfer

12. Monoclonal Antibodies in the Treatment of Malignant Lymphomas
Bertrand Coiffier

13. Molecular Network Analysis using Reverse Phase Protein Microarrays for Patient Tailored Therapy
Runa Speer, Julia Wulfkuhle, Virginia Espina, Robyn Aurajo, Kirsten H. Edmiston, Lance A. Liotta, Emanuel F. Petricoin

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Avainsanat: TECHNOLOGY & ENGINEERING / Biomedical TEC059000