Fink, Anthony L.
Protein Misfolding, Aggregation, and Conformational Diseases
I.Altered Protein Structure and Enhanced Aggregation/Deposition
1. The Pathogenesis of Alzheimer’s Disease: General Overview
Liana G. Apostolova, Jeffrey L. Cummings
2. Free Radicals, Metal Ions, and Aß Aggregation and Neurotoxicity
Kevin J. Barnham, Cyril C. Curtain, Ashley I. Bush
3. Progress in Understanding the Mechanisms of Neuronal Dysfunction and Degeneration in Parkinson’s Disease
J. William Langston
4. a-Synuclein Aggregation and Parkinson’s Disease
Vladimir N. Uversky
5. Cell Biology of
Seung-Jae Lee, Yoon Suk Kim
6. Pathogenesis of Prion Diseases
Giuseppe Legname, Stephen J. DeArmond, Fred E. Cohen, Stanley B. Prusiner
7. Mammalian Prion Protein
Ilia V. Baskakov
8. The Yeast Prion Proteins Sup35p and Ure2p
Joanna Krzewska, Ronald Melki
9. Immunoglobulin Light Chain and Systemic Light-Chain Amyloidosis
Marina Ramirez-Alvarado, Janelle K. Stigter, Elizabeth M. Baden, Laura A. Sikkink, Richard W. McLaughlin, Anya L. Taboas
10. Pancreatic Islet Amyloid and Diabetes
Anne Clark, Jenni Moffitt
11. ß
Isobel J. Morten, Eric W. Hewitt, Sheena E. Radford
12. Serum Amyloid A and AA Amyloidosis
Zafer Ali-Khan
II.Point Mutations and Enhanced Protein Deposition
13. Transthyretin and the Transthyretin Amyloidoses
Joel N. Buxbaum
14. Human Lysozyme
Mireille Dumoulin, Russell J. K. Johnson, Vittorio Bellotti, Christopher M. Dobson
15. Serpins and the Diversity of Conformational Diseases
Robin W. Carrell
III.Altered Protein Structure and Impaired Function
16. Human Copper-Zinc Superoxide Dismutase and Familial Amyotrophic Lateral Sclerosis
Ahmad Galaleldeen, P. John Hart
17. Understanding the Effects of Cancer-Associated Mutations in the Tumor Suppressor Protein p53: Structural Consequences of Mutations and Possible Ways of Rescuing Oncogenic Mutants
Andreas C. Joerger, Assaf Friedler, Alan R. Fersht
IV.Changes in Supramolecular Structure
18. Protein Aggregation in Muscle Fibers and Respective Neuromuscular Disorders
Alexandra Vrabie, Hans H. Goebel
19. Muscular Dystrophies and Protein Mutations
Mariz Vainzof, Mayana Zatz
20. The Functional Consequences of Dystrophin Deficiency in Skeletal Muscles
Jean-Marie Gillis
21. Eye Lens Proteins and Cataracts
Roger John Willis Truscott
V.Altered Protein Structure and Changes in Cellular/Nuclear Function
22. Glutamine/Asparagine-Rich Regions in Proteins and Polyglutamine Diseases
Hitoshi Okazawa
23. Mechanistic Insights into the Polyglutamine Ataxias
Victor M. Miller, Henry L. Paulson
24. Molecular Pathogenesis of the Polyglutamine Disease: Spinal and Bulbar Muscular Atrophy
Erica S. Chevalier-Larsen, Diane E. Merry
VI.Post-Translational Modification and Protein Conformational Diseases
25. Protein Glycation and Cataract: A Conformational Disease
John J. Harding
26. Defective Glycosylation and Muscular Dystrophies
Paul T. Martin
DRM-restrictions
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Avainsanat: TECHNOLOGY & ENGINEERING / Biomedical TEC059000
- Tekijä(t)
- Fink, Anthony L.
- Uversky, Vladimir N.
- Julkaisija
- Springer
- Julkaisuvuosi
- 2007
- Kieli
- en
- Painos
- 1
- Kategoria
- Terveys, kauneus, muoti
- Tiedostomuoto
- E-kirja
- eISBN (PDF)
- 9780387365343