Peptide Nucleic Acids, Morpholinos and Related Antisense Biomolecules

Part I.Research Applications

1. The Many Faces of PNA
Peter E. Nielsen

2. Modulation of Nucleic Acid Information Processing by PNAs
Lionel Bastide, Bernard Lebleu, Ian Robbins

3. Targeted Gene Delivery
Kenneth W. Liang, Feng Liu, Leaf Huang

4. Imaging Gene Expression in the Brain with Peptide Nucleic Acid (PNA) Antisense Radiopharmaceuticals and Drug Targeting Technology
Ruben J. Boado, William M. Pardridge

5. Receptor-Specific Targeting with Complementary Peptide Nucleic Acids Conjugated to Peptide Analogs and Radionuclides
Eric Wickstrom, Mathew L. Thakur, Edward R. Sauter

6. Morpholinos and PNAs Compared
James E. Summerton

7. Chemistry of Locked Nucleic Acids (LNA)
Jesper Wengel, Michael Petersen, Miriam Frieden, Troels Koch

8. Recent Applications of RNA Interference (RNAi) in Mammalian Systems
Lisa Scherer, John J. Rossi

Part II.Clinical Applications

9. Peptide Nucleic Acids as Epigenetic Inhibitors of HIV-1
Shizuko Sei

10. Therapeutic Uses of Peptide Nucleic Acids (PNA) in Oncology
Nadia Zaffaroni, Raffaella Villa, Marco Folini

11. PNAs as Novel Cancer Therapeutics
Luca Mologni, Carlo Gambacorti-Passerini

12. Medicinal Chemistry of Plasmid DNA with Peptide Nucleic Acids
Olivier Zelphati, Jiin Felgner, Yan Wang, Xiaowu Liang, Xiaodong Wang, Philip Felgner

13. Locked Nucleic Acids (LNA) and Medical Applications
Henrik Ørum, Andreas Wolter, Lars Kongsbak

14. Peptide Nucleic Acids as Agents to Modify Target Gene Expression and Function
Gan Wang, Peter M. Glazer

15. Peptide Nucleic Acids
David R. Corey

16. The Use of PNAs and Their Derivatives in Mitochondrial Gene Therapy
Paul M. Smith, Günther F. Ross, Theresa M. Wardell, Robert W. Taylor, Douglass M. Turnbull, Robert N. Lightowlers

17. Gene Silencing through RNA Interference
David O. Azorsa, Spyro Mousses, Natasha J. Caplen

18. Transcriptional Activation of Human CREB Gene Promoter Using Bis-PNA (Peptide Nucleic Acid)
Christopher G. Janson, Matthew J. During, Yelena Shifman, Paola Leone

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Avainsanat: TECHNOLOGY & ENGINEERING / Biomedical TEC059000