Protein Misfolding, Aggregation, and Conformational Diseases

1. Structural and Conformational Prerequisites of Amyloidogenesis
Vladimir N. Uversky, Ariel Fernández, Anthony L. Fink

2. The Generic Nature of Protein Folding and Misfolding
Christopher M. Dobson

3. Relative Importance of Hydrophobicity, Net Charge, and Secondary Structure Propensities in Protein Aggregation
Fabrizio Chiti

4. Cytotoxic Intermediates in the Fibrillation Pathway: Aß Oligomers in Alzheimer’s Disease as a Case Study
William L. Klein

5. Glycosaminoglycans, Proteoglycans, and Conformational Disorders
Gregory J. Cole, I.-Hsuan Liu

6. Apolipoproteins in Different Amyloidoses
Marcin Sadowski, Thomas Wisniewski

7. Oxidative Stress and Protein Deposition Diseases
Joseph R. Mazzulli, Roberto Hodara, Summer Lind, Harry Ischiropoulos

8.Chaperone and Conformational Disorders

8. Chaperone Suppression of Aggregated Protein Toxicity
Jennifer L. Wacker, Paul J. Muchowski

9. Mechanisms of Active Solubilization of Stable Protein Aggregates by Molecular Chaperones
Pierre Goloubinoff, Anat Peres Ben-Zvi

10. The Aggresome: Proteasomes, Inclusion Bodies, and Protein Aggregation
Jennifer A. Johnston

11. Protein Aggregation, Ion Channel Formation, and Membrane Damage
Bruce L. Kagan

11.Visualization of Protein Deposits In Vivo

12. Congo Red Staining of Amyloid: Improvements and Practical Guide for a More Precise Diagnosis of Amyloid and the Different Amyloidoses
Reinhold P. Linke

13. Immunohistological Study of Experimental Murine AA Amyloidosis
Mie Kuroiwa, Kimiko Aoki, Naotaka Izumiyama

12.Visualization of Protein Deposits In Vitro

14. Reporters of Amyloid Structure
Harry LeVine

15. Three-Dimensional Structural Analysis of Amyloid Fibrils by Electron Microscopy
Sara Cohen-Krausz, Helen R. Saibil

16. Atomic Force Microscopy
Justin Legleiter, Tomasz Kowalewski

17. Direct Observation of Amyloid Fibril Growth Monitored by Total Internal Reflection Fluorescence Microscopy
Tadato Ban, Yuji Goto

13.Animal and Cell Models of Human Neurodegenerative Disorders

18. Drosophila and C. elegans Models of Human Age-Associated Neurodegenerative Diseases
Julide Bilen, Nancy M. Bonini

19. Genetically Engineered Mouse Models of Neurodegenerative Disorders
Eliezer Masliah, Leslie Crews

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Avainsanat: TECHNOLOGY & ENGINEERING / Biomedical TEC059000