Regulation of Signal Transduction in Human Cell Research

1. Using Genetically Engineered Mouse Models to Study Wnt Signaling in Bone Development and Disease
Zhendong A. Zhong, Nicole J. Ethen, Bart O. Williams

2. Role of theReceptor-Mediated Signaling Pathways on theProliferation and Differentiation of Pluripotent Stem Cells
Toshiaki Ishizuka

3. Regulation of microRNA Expression byGrowth Factors in Tumor Development and Progression
Hiroshi Itoh, Sotai Kimura, Seiji Naganuma

4. Regulation of EMT by TGF-β Signaling in Cancer Cells
Masao Saitoh

5. The Functional Interplay Between Pro-oncogenic RUNX2 and Hypoxia-Inducible Factor-1α (HIF-1α) During Hypoxia-Mediated Tumor Progression
Toshinori Ozaki, Mizuyo Nakamura, Takehiko Ogata, Meijie Sang, Osamu Shimozato

6. DNA Damage: Cellular Responses, Repair, and Cancer Treatment
Brian M. Cartwright, Phillip R. Musich, Yue Zou

7. Met Activation and Carcinogenesis
Nariyoshi Shinomiya, Qian Xie, George F. Vande Woude

8. The HGF/MET Signaling and Therapeutics in Cancer
Douglas P. Thewke, Jianqun Kou, Makenzie L. Fulmer, Qian Xie

9. Pericellular Activation of Peptide Growth Factors by Serine Proteases
Hiroaki Kataoka, Tsuyoshi Fukushima

10. Molecular Designing of Small-Molecule Inhibitors for Apoptosis Regulation
Atsushi Yoshimori, Sei-Ichi Tanuma

Keywords: Medicine & Public Health, Oncology, Medical Biochemistry, Cancer Research