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Li, Long-Cheng

RNA Activation

Li, Long-Cheng - RNA Activation, ebook

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ISBN: 9789811043109
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Table of contents

1. Small RNA-Guided Transcriptional Gene Activation (RNAa) in Mammalian Cells
Long-Cheng Li

Part I. Exogenous RNAa

2. Enhancing Neuronogenesis and Counteracting Neuropathogenic Gene Haploinsufficiencies by RNA Gene Activation
Antonello Mallamaci

3. Target-Recognition Mechanism and Specificity of RNA Activation
Huiqing Cao, Xing Meng, Xiaoxia Wang, Zicai Liang

4. Promoter-Targeted Small Activating RNAs Alter Nucleosome Positioning
Bin Wang, Yunzhang Hu

Part II. Endogenous RNAa

5. Endogenous miRNAa: miRNA-Mediated Gene Upregulation
Vera Huang

6. miRNA-Mediated RNA Activation in Mammalian Cells
Ramani Ramchandran, Pradeep Chaluvally-Raghavan

7. RNAa Induced by TATA Box-Targeting MicroRNAs
Yijun Zhang, Hui Zhang

8. miRNA-Mediated RNAa by Targeting Enhancers
Qingping Zou, Ying Liang, Huaibing Luo, Wenqiang Yu

Part III. RNA Activation Guided by Other Small RNAs

9. Specific Increase of Protein Levels by Enhancing Translation Using Antisense Oligonucleotides Targeting Upstream Open Frames
Xue-Hai Liang, Wen Shen, Stanley T. Crooke

10. Repurposing CRISPR System for Transcriptional Activation
Meng Chen, Lei Stanley Qi

Part IV. Developing RNAa-Based Therapeutics

11. RNA-Mediated Gene Activation: Identifying a Candidate RNA for Preclinical Development
David R. Corey

12. Treatment of Pancreatic Cancer by Aptamer Conjugated C/EBPα-saRNA
Sorah Yoon, John J. Rossi

13. Treatment of Liver Cancer by C/EBPA saRNA
Xiaoyang Zhao, Jon Voutila, Stephanos Ghobrial, Nagy A. Habib, Vikash Reebye

14. Enhancing Angiogenesis in Mice by VEGF-Targeting Small Activating RNAs
Tiia A. Turunen, Seppo Ylä-Herttuala, Mikko P. Turunen

15. Suppression of Prostate Cancer Metastasis by DPYSL3-Targeted saRNA
Benyi Li, Changlin Li

16. Development of Therapeutic dsP21-322 for Cancer Treatment
Moo Rim Kang, Gongcheng Li, Tiejun Pan, Jin-Chun Xing, Long-Cheng Li

Keywords: Biomedicine, Gene Expression, Biochemistry, general, Cell Biology, Molecular Medicine, Cancer Research

Editor
Publisher
Springer
Publication year
2017
Language
en
Edition
1
Series
Advances in Experimental Medicine and Biology
Category
Medicine, Health Care, Mode
Format
Ebook
eISBN (PDF)
9789811043109
Printed ISBN
978-981-10-4309-3

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