New Horizons of Process Chemistry

1. Recent Advances in Rare Earth Metal Asymmetric Catalysis Toward Practical Synthesis of Therapeutics
Naoya Kumagai, Masakatsu Shibasaki

2. Metal Catalyzed Synthetic Reactions via Aerobic Oxidation as a Key Step
Mitsuru Shindo, Kenji Matsumoto

3. Heterogeneous Platinum Metal Catalyzed Deuterium Generation and Labeling Methods Using Hydrogen Gas and Deuterium Oxide as Key Reagents
Hironao Sajiki

4. Pd on Spherical Carbon (Pd/SC)-Catalyzed Chemoselective Hydrogenation
Hiroyoshi Esaki

5. Environment-Friendly Iron-Catalyzed Reactions
Yoshinari Sawama

6. Tetranuclear Zinc Cluster-Catalyzed Transesterification
Takashi Ohshima

7. Vinyl Ruthenium Carbenes: Valuable Intermediates in Catalysis
Damián Padín, Jesús A. Varela, Carlos Saá

8. Radical-Based Late Stage C–H Functionalization of Heteroaromatics in Drug Discovery
Yuta Fujiwara, Phil S. Baran

9. Magnetic Nanoparticle-Supported Iodoarene Oxidative Catalysts and Its Application to Phenol Oxidation
Hisanori Nambu, Ikumi Shimokawa, Tomoya Fujiwara, Takayuki Yakura

10. Recent Development of Diphenyl Phosphorazidate (DPPA) as a Synthetic Reagent
Takayuki Shioiri

11. Methylenation Reaction of Carbonyl Compounds Using Julia-Kocienski Reagents
Kaori Ando

12. Development of Shelf-Stable Reagents for Electrophilic Trifluoromethylthiolation Reaction
Zhongyan Huang, Norio Shibata

13. Practical and Environmentally Friendly Transformation of Tetrahydrofuran-2-Methanols to γ-Lactones via Oxidative Cleavage
Tomoya Fujiwara, Yuto Horiuchi, Akihiro Yamada, Hisanori Nambu, Takayuki Yakura

14. Five Step Asymmetric Total Synthesis of β-Lycorane Employing Chiral Diether Ligand-Controlled Conjugate Addition-Michael Reaction Cascade
Kiyoshi Tomioka

15. Concise Synthesis of Peptide Analogs Using a Fluorous-Fmoc Protection Strategy
Masato Matsugi

16. A Challenging Synthesis of the Highly Functionalized Echinocandin ASP9726: A Successor of Micafungin—How Can We Achieve the Large-Scale Synthesis?
Shinya Yoshida, Joji Hayashida, Yasuhiro Morinaga, Shoji Mizobata, Akihiro Okada, Kazumi Kawai, Shinjirou Tanoue, Tomohide Nakata, Minoru Kitayama, Atsushi Ohigashi, Mitsutaka Matsuura, Takumi Takahashi, Shigeru Ieda, Minoru Okada

17. The Role of Silyl Protecting Group for the Synthesis of Procyanidins and Their Derivatives
Noriyuki Nakajima, Akiko Saito

18. Chemical Modification of the 3′-Dangling End of Small Interfering RNAs Such as siRNAs and miRNAs: The Development of miRNA Replacement Therapy
Yukio Kitade, Takashi Mori, Yukihiro Akao

19. Antiviral Agents Towards Chikungunya Virus: Structures, Syntheses, and Isolation from Natural Sources
Jih Ru Hwu, Tapan K. Pradhan, Shwu-Chen Tsay, Mohit Kapoor, Sergey O. Bachurin, Oleg A. Raevsky, Johan Neyts

20. Analytical Standards Purity Determination Using Quantitative Nuclear Magnetic Resonance
Toru Miura, Naoki Sugimoto, Takako Suematsu, Kevin K. Millis, Katsuo Asakura, Yuko Yamada

Keywords: Chemistry, Industrial Chemistry/Chemical Engineering, Organic Chemistry, Pharmacy, Agriculture, Catalysis