Topics in Biomedical Gerontology

Part I. Models and Markers in Aging

1.
Drosophila melanogaster: A Prime Experimental Model System for Aging Studies
Renu Yadav, Soram Idiyasan Chanu, Kritika Raj, Nisha, Surajit Sarkar

2.
Dictyostelium discoideum: A Model System to Study Autophagy Mediated Life Extension
Punita Jain, Priyanka Sharma, Anju Shrivastava, Shweta Saran

3. Down Regulation of Sirtuins in the Serum of Frail Elderly as Compared to Non-frail Elderly: Promising Diagnostic Protein Marker for Frailty
Sharmistha Dey

4. Morphology of the Human Pancreas During Development and Aging
Renu Gupta, Shubhi Saini, Saroj Sharma, Tony G. Jacob, T. S. Roy

Part II. Metabolic and Molecular Changes in Aging

5. Insulin-like Growth Factor-1 and Its Related Signalling During Aging: Modulation by Dietary Restriction
Ibanylla Kynjai Hynniewta Hadem, Ramesh Sharma

6. Arginase I Regulation by Dexamethasone in the Liver of Aging Mouse
Teikur Majaw, Ramesh Sharma

7. Inorganic Pyrophosphatase of Cardiac and Skeletal Muscle is Enhanced by Dietary Restriction in Mice During Aging
Wanaiborlang Jala Kharbhih, Ramesh Sharma

8. Oxidative Stress and the Brain: An Insight into Cognitive Aging
Sambe Asha Devi, Abhijit Satpati

9. Age-Related Changes in Antioxidant Enzymes of Rat Kidney and Oxidative Stress Parameters with Special Reference to Methylation of the Catalase Promoter
Srikanta Jena, Suresh K. Bunker, Jagneshwar Dandapat, G. B. N. Chainy

10. Differential Expression of Long Noncoding RNA in the Rat Brain During Aging
Sukhleen Kour, Pramod C. Rath

11. Chromatin and Aging
Jogeswar Satchidananda Purohit, Madan Mohan Chaturvedi

Part III. Neuromodulations in Aging

12. Changing Population of Neurons and Glia in the Human Cochlear Nucleus During Aging
Saroj Sharma, Tony G. Jacob, Tapas C. Nag, Daya N. Bhardwaj, T. S. Roy

13. Changes in Social Behavior Associated with Alzheimer’s Disease-Related Aβ Pathology
Neha Mishra, Rameshwar Singh, Deepak Sharma

14. Recovery of Age-Related Memory Loss: Hopes and Challenges
Mahendra Kumar Thakur, Arpita Konar, Dhiraj Kumar, Meghraj Singh Baghel, Padmanabh Singh

15. Expression and Regulation of Pax6 in Brain of Aging Mice
Shashank Kumar Maurya, Ratnakar Tripathi, Suman Mishra, Rajnikant Mishra

16. Electrophysiological Ageing of the Brain: Ageing-Related Impairments in Neural and Cognitive Functions
Rameshwar Singh

17. Antiaging Neurosteroid Dehydroepiandrosterone Counters Epileptiform Activity in Iron-Induced Experimental Epilepsy
Monika Mishra, Rameshwar Singh, Deepak Sharma

Part IV. Interventions for Healthy Aging

18. The Holistic Principles of Ayurvedic Geriatrics
Ram H. Singh

19. Dietary Restriction, an Intervention for Healthy Aging
Ramesh Sharma

20. Diabetes Mellitus Type 2 Induces Brain Aging and Memory Impairment in Mice: Neuroprotective Effects of Bacopa monnieri Extract
Surya Prakash Pandey, S. Prasad

Keywords: Medicine & Public Health, Geriatrics/Gerontology, Regenerative Medicine/Tissue Engineering, Geriatric Care, Human Genetics, Metabolomics, Molecular Medicine