Molecular Targeted Therapy of Lung Cancer

Part I. Diagnosis

1. Classification of Adenocarcinoma of the Lung, with a Special Reference to Prognosis
Yukio Nakatani, Yoko Yonemori, Jun Matsushima, Takuya Yazawa

2. Screening Lung Cancer with Low-Dose CT Combined with Molecular Markers
Yuichi Takiguchi

3. PET-CT, Bio-imaging for Predicting Prognosis and Response to Chemotherapy in Patients with Lung Cancer
Kyoichi Kaira

4. Methods in Molecular Diagnosis
Koichi Hagiwara

5. Accurate Nodal Staging and Biomarker Testing with Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration
Takahiro Nakajima, Ichiro Yoshino

6. Next-Generation Sequencing and Bioinformatics
Reika Kawabata-Iwakawa, Hidemasa Bono, Masahiko Nishiyama

7. Companion Diagnostics
Emi Noguchi

Part II. Treatment

8. Small Cell Lung Cancer and Molecular Targeted Therapy
Shunichiro Iwasawa

9. Locally Advanced Non-small Cell Lung Cancer and Targeted Therapy
Ikuo Sekine

10. EGFR Mutant
Kunihiko Kobayashi, Hiroshi Kagamu

11. ALK Mutant
Akihiko Gemma

12. Minor-Driver Mutant
Akihiko Miyanaga

13. Mechanism of Resistance to Targeted Molecular Therapy
Masahiro Seike

14. Immunotherapy
Takahiro Ebata

15. Lung Cancer Complicated with Interstitial Lung Diseases
Yuji Minegishi

16. Management of Adverse Effects by Molecular Targeted Therapy and Immunotherapy
Toshimichi Miya

Part III. Evaluation

17. Health-Related Quality of Life in Molecular Targeted Therapy
Shinji Nakamichi, Kaoru Kubota

18. Gene Signature
Hideki Ujiie, Daiyoon Lee, Tatsuya Kato, Kazuhiro Yasufuku

Part IV. Novel Approach

19. Targeting Epithelial-Mesenchymal Transition and Cancer Stem Cell
Ryota Kurimoto, Yuichi Takiguchi

20. Targeting the Lung Cancer Microenvironment: Harnessing Host Responses
Mark M. Fuster

Keywords: Medicine & Public Health, Pneumology/Respiratory System, Oncology, Molecular Medicine