Pediatric Biomedical Informatics

Part I. Core Informatics Resources

1. Electronic Health Records in Pediatrics
S. Andrew Spooner, Eric S. Kirkendall

2. Protecting Privacy in the Child Health EHR
S. Andrew Spooner

3. Standards for Interoperability
S. Andrew Spooner, Judith W. Dexheimer

4. Data Storage and Access Management
Michal Kouril, Michael Wagner

5. Institutional Cybersecurity in a Clinical Research Setting
Michal Kouril, John Zimmerly

6. Data Governance and Strategies for Data Integration
Keith Marsolo, Eric S. Kirkendall

7. Laboratory Medicine and Biorepositories
Paul E. Steele, John A. Lynch, Jeremy J. Corsmo, David P. Witte, John B. Harley, Beth L. Cobb

Part II. Clinical Applications

8. Informatics for Perinatal and Neonatal Research
Eric S. Hall

9. Clinical Decision Support and Alerting Mechanisms
Judith W. Dexheimer, Philip Hagedorn, Eric S. Kirkendall, Michal Kouril, Thomas Minich, Rahul Damania, Joshua Courter, S. Andrew Spooner

10. Informatics to Support Learning Networks and Distributed Research Networks
Keith Marsolo

11. Natural Language Processing – Overview and History
Brian Connolly, Timothy Miller, Yizhao Ni, Kevin B. Cohen, Guergana Savova, Judith W. Dexheimer, John Pestian

12. Natural Language Processing: Applications in Pediatric Research
Guergana Savova, John Pestian, Brian Connolly, Timothy Miller, Yizhao Ni, Judith W. Dexheimer

13. Network Analysis and Applications in Pediatric Research
Hailong Li, Zhaowei Ren, Sheng Ren, Xinyu Guo, Xiaoting Zhu, Long Jason Lu

Part III. Genomic Applications

14. Genetic Technologies and Causal Variant Discovery
Phillip J. Dexheimer, Kenneth M. Kaufman, Matthew T. Weirauch

15. Precision Pediatric Genomics: Opportunities and Challenges
Kristen L. Sund, Peter White

16. Bioinformatics and Orphan Diseases
Anil G. Jegga

17. Toward Pediatric Precision Medicine: Examples of Genomics-Based Stratification Strategies
Jacek Biesiada, Senthilkumar Sadhasivam, Mojtaba Kohram, Michael Wagner, Jaroslaw Meller

18. Application of Genomics to the Study of Human Growth Disorders
Michael H. Guo, Andrew Dauber

19. Systems Biology Approaches for Elucidation of the Transcriptional Regulation of Pulmonary Maturation
Yan Xu, Jeffrey A. Whitsett

20. Functional Genomics-Renal Development and Disease
S. Steven Potter

Keywords: Biomedicine, Biomedicine general, Computational Biology/Bioinformatics, Health Informatics, Biostatistics