Translational Bioinformatics and Its Application

Part I. Computer-Aided Drug Discovery

1. Drug Discovery
Geetha Ramakrishnan

2. Translational Bioinformatics and Drug Discovery
Pramodkumar Pyarelal Gupta

3. Translational Research in Drug Discovery and Development
Neha Arora, Pawan Kumar Maurya, Puneet Kacker

4. Exploring the Potential of Herbal Ligands Toward Multidrug-Resistant Bacterial Pathogens by Computational Drug Discovery
Sinosh Skariyachan

Part II. Protein-Ligand Interactions and Drug Development

5. The Progress of New Targets of Anti-HIV and Its Inhibitors
Ke Z. Wu, Ai X. Li

6. Recent Studies on Mechanisms of New Drug Candidates for Alzheimer’s Disease Interacting with Amyloid-β Protofibrils Using Molecular Dynamics Simulations
Huai-Meng Fan, Qin Xu, Dong-Qing Wei

7. Homology Modelling, Structure-Based Pharmacophore Modelling, High-Throughput Virtual Screening and Docking Studies of L-Type Calcium Channel for Cadmium Toxicity
Madhu Sudhana Saddala, A. Usha Rani

8. Natural Compounds Are Smart Players in Context to Anticancer Potential of Receptor Tyrosine Kinases: An In Silico and In Vitro Advancement
Pushpendra Singh, Shashank Kumar, Felix Bast

Part III. Omics for Precision Medicine

9. Genome-Wide Association Studies: A Comprehensive Tool to Explore Comparative Genomic Variations and Interactions
Aruni Wilson

10. A Survey of Bioinformatics-Based Tools in RNA-Sequencing (RNA-Seq) Data Analysis
Pallavi Gaur, Anoop Chaturvedi

11. Epigenetics and Its Role in Human Cancer
Utkarsh Raj, Pritish Kumar Varadwaj

12. Methods for Microbiome Analysis
Kalibulla Syed Ibrahim, Nachimuthu Senthil Kumar

13. Pharmacogenomics: Clinical Perspective, Strategies, and Challenges
Dev Bukhsh Singh

Part IV. Biostatistics, Bioinformatics, and System Biology Approaches to Complex Diseases

14. Computational Network Approaches and Their Applications for Complex Diseases
Ankita Shukla, Tiratha Raj Singh

15. Bioinformatics Applications in Clinical Microbiology
Chao Zhang, Shunfu Xu, Dong Xu

Part V. Bioimaging and Other Applications of Informatics Techniques in Translational Medicine

16. Artificial Intelligence and Automatic Image Interpretation in Modern Medicine
Costin Teodor Streba, Mihaela Ionescu, Cristin Constantin Vere, Ion Rogoveanu

17. Computation in Medicine: Medical Image Analysis and Visualization
Adekunle Micheal Adeshina

Keywords: Life Sciences, Bioinformatics, Human Genetics, Biostatistics, Health Informatics