Essentials of Mesenchymal Stem Cell Biology and Its Clinical Translation

Part I. Basic Research/Mechanisms

1. A Historical Overview and Concepts of Mesenchymal Stem Cells
Shihua Wang, Robert Chunhua Zhao

2. Biology of MSCs Isolated from Different Tissues
Simone Pacini

3. Secretome of Mesenchymal Stem Cells
Yuan Xiao, Xin Li, Hong Hao, Yuqi Cui, Minjie Chen, Lingjun Liu, Zhenguo Liu

4. Immunomodulatory Properties of Mesenchymal Stem Cells and Related Applications
Lianming Liao, Robert Chunhua Zhao

5. Mesenchymal Stem Cell Homing to Injured Tissues
Yaojiong Wu, Robert Chunhua Zhao

6. Major Signaling Pathways Regulating the Proliferation and Differentiation of Mesenchymal Stem Cells
Joseph D. Lamplot, Sahitya Denduluri, Xing Liu, Jinhua Wang, Liangjun Yin, Ruidong Li, Wei Shui, Hongyu Zhang, Ning Wang, Guoxin Nan, Jovito Angeles, Lewis L. Shi, Rex C. Haydon, Hue H. Luu, Sherwin Ho, Tong-Chuan He

7. MicroRNAs in Mesenchymal Stem Cells
Mohammad T. Elnakish, Ibrahim A. Alhaider, Mahmood Khan

8. Genetic Modification of MSCs for Pharmacological Screening
Jie Qin, Martin Zenke

9. Control of Mesenchymal Stem Cells with Biomaterials
Sandeep M. Nalluri, Michael J. Hill, Debanjan Sarkar

Part II. Clinical Translation

10. Mesenchymal Stem Cells for Cardiovascular Disease
Wei Wu, Shuyang Zhang

11. Mesenchymal Stem Cells as Therapy for Graft Versus Host Disease: What Have We Learned?
Partow Kebriaei, Simon Robinson, Ian McNiece, Elizabeth Shpall

12. Mesenchymal Stem Cells for Liver Disease
Feng-chun Zhang

13. Mesenchymal Stem Cells for Bone Repair
Hongwei Ouyang, Xiaohui Zou, Boon Chin Heng, Weiliang Shen

14. Mesenchymal Stem Cells for Diabetes and Related Complications
Vladislav Volarevic, Majlinda Lako, Miodrag Stojkovic

15. Mesenchymal Stromal Cell (MSC) Therapy for Crohn’s Disease
Jignesh Dalal

16. The Summary of Stroke and Its Stem Cell Therapy
Renzhi Wang, Ming Feng, Xinjie Bao, Jian Guan, Yang liu, Jin Zhang

17. Mesenchymal Stem Cell Transplantation for Systemic Lupus Erythematosus
Lingyun Sun

Part III. International Regulations and Guidelines Governing Stem Cell Based Products

18. Considerations of Quality Control Issues for the Mesenchymal Stem Cells-Based Medicinal Products
Bao-Zhu Yuan, Debanjan Sarkar, Simone Pacini, Mahmood Khan, Miodrag Stojkovic, Martin Zenke, Richard Boyd, Armand Keating, Eric Raymond, Robert Chunhua Zhao

19. Regulations/Ethical Guidelines on Human Adult/Mesenchymal Stem Cell Clinical Trial and Clinical Translation
Xiaomei Zhai, Renzong Qiu

Keywords: Life Sciences, Cell Biology, Stem Cells, Internal Medicine, Pathology