Hayat, M.A.

Tumor Dormancy, Quiescence, and Senescence, Volume 1

Hayat, M.A. - Tumor Dormancy, Quiescence, and Senescence, Volume 1, ebook


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Table of contents

Part I. Tumor Dormancy

1. Dormancy, Quiescence, and Cellular Senescence
M. A. Hayat

2. Is Tumor Dormancy Clinically Relevant?
Dieter Hölzel, Renate Eckel, Rebecca Emeny, Jutta Engel

3. Microenvironmental Influence on Breast Cancer Dormancy and Metastasis
George R. Nahas, Jacqueline M. Park, Pranela Rameshwar

4. Determination of Breast Cancer Dormancy: Analysis of Circulating Free DNA Using SNP 6.0 Arrays
Jacqui Shaw, Kevin Blighe, Karen Page, David Guttery, R. Charles Coombes

5. Clonogenicity of Cultured Prostate Cancer Cells Is Controlled by Dormancy: Significance and Comparison with Cell Culture Models of Breast Cancer Cell Dormancy
Thierry Tchénio

6. Dormancy and Metastasis of Melanoma Cells to Lymph Nodes, Lung and Liver
Vincent L. Morris, Dean B. Percy, Michael M. Lizardo, Ann F. Chambers, Ian C. MacDonald

7. Late Recurrence Is a Sign of Melanoma Dormancy: Need of Life-Long Follow-Up of Melanoma Patients
Uwe Wollina

Part II. Quiescence

8. Hematopoietic Stem Cell Quiescence and Long Term Maintenance: Role of SCL/TAL1
Shanti Rojas-Sutterlin, Trang Hoang

9. Regulation of Muscle Stem Cell Quiescent and Undifferentiated State: Roles of Hesr1 and Hesr3 Genes
Masahiko Yamaguchi, So-ichiro Fukada

10. The Kinase MIRK/DYRK1B Mediates a Reversible Quiescent State in a Subset of Ovarian, Pancreatic and Colon Cancers
Eileen A. Friedman

Part III. Cellular Senescence

11. Stress-Induced Senescence: Molecular Pathways
Peter J. Hornsby

12. Accumulation of Reactive Oxygen Species and Induction of Premature Senescence: Role of DDB2
Nilotpal Roy, Pradip Raychaudhuri

13. p21 Mediates Senescence by a Mechanism Involving Accumulation of Reactive Oxygen Species
Ionica Masgras, Salvador Macip

14. Role of MicroRNAs and ZEB1 Downmodulation in Oxidative Stress-Induced Apoptosis and Senescence
Alessandra Magenta, Maurizio C. Capogrossi

15. Hypoxic Response in Senescent Brain Is Impaired: Possible Contribution to Neurodegeneration
Tamer Rabie

16. Enhancing Reprogramming to Pluripotency by Controlling Senescence
Ana Banito, Jesús Gil

17. Histone Deacetylase Inhibitor Induces Replicative Senescence of Mesenchymal Stem Cells
Seunghee Lee, Ji-Won Jung, Kyung-Sun Kang

18. Senescence Arrest of Endopolyploid Cells Renders Senescence into One Mechanism for Positive Tumorigenesis
Kirsten H. Walen

19. The Two Faces of Senescence-Associated Epigenetic Alterations: Tumor Suppressors and Oncogenic Drivers
Anabelle Decottignies

20. Chemotherapy- and Radiation-Induced Accelerated Senescence: Implications for Treatment Response, Tumor Progression and Cancer Survivorship
Molly L. Bristol, Lynne W. Elmore

21. Suppression of Cellular Senescence in Glioblastoma: Role of Src Homology Domain-Containing Phosphatase 2
Lisa-Marie Sturla, Pascal Zinn, Ekkehard Kasper

22. Chemotherapy of Malignant Pleural Mesothelioma Induces Both Senescence and Apoptosis
Emanuela Felley-Bosco, Rolf A. Stahel

23. MicroRNA as a Modulator of Cell Proliferation and Senescence: Role in Lung Cancer Cells
Sayuri Fukui, Masaki Sekiguchi, Kenichi Miyata, Hiroaki Ohdaira, Kenichi Yoshida

24. Role of Senescence Induction in Cancer Therapy
Hiroshi Kondoh, Takumi Mikawa, Matilde E. LLeonart

25. Cellular Senescence Limits the Extent of Fibrosis Following Liver Damage
Valery Krizhanovsky

26. Formation of Secretory Senescent Cells in Prostate Tumors: The Role of Androgen Receptor Activity and Cell Cycle Regulation
Zuzana Pernicová, Petr Vaňhara, Karel Souček

Keywords: Biomedicine, Cancer Research, Stem Cells, Public Health

Publication year
Tumor Dormancy and Cellular Quiescence and Senescence
Page amount
24 pages
Medicine, Health Care, Mode

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