Applied Computational Genomics

1. Introduction
Yin Yao Shugart, Andrew Collins

2. Concepts of Genetic Epidemiology
Kathleen Ries Merikangas

3. Integration of Linkage Analysis and Next-Generation Sequencing Data
Francesca Lantieri, Mark A. Levenstien, Marcella Devoto

4. From Family Study to Population Study: A History of Genetic Mapping for Nasopharyngeal Carcinoma (NPC)
Timothy J. Jorgensen, Hai-De Qin, Yin Yao Shugart

5. QTL Mapping of Molecular Traits for Studies of Human Complex Diseases
Chunyu Liu

6. Renewed Interest in Haplotype: From Genetic Marker to Gene Prediction
Shuying Sue Li, Xinyi Cindy Zhang, Lue Ping Zhao

7. Analytical Approaches for Exome Sequence Data
Andrew Collins

8. Rare Variants Analysis in Unrelated Individuals
Tao Feng, Xiaofeng Zhu

9. Gene Duplication and Functional Consequences
Xun Gu, Yangyun Zou, Zhixi Su

10. From GWAS to Next-Generation Sequencing on Human Complex Diseases: The Implications for Translational Medicine and Therapeutics
Hai-De Qin, Alan Scott, Harold Z. Wang, Yin Yao Shugart

Keywords: Biomedicine, Human Genetics, Bioinformatics, Biotechnology