MicroRNAs as Tools in Biopharmaceutical Production

1. A General Introduction to MicroRNAs, Their Investigation and Exploitation in CHO Cell Lines
Lyne Jossé, Lin Zhang, C Mark Smales

2. Biogenesis of Mammalian miRNA
Stephen L. Clarke, McKale R. Davis, Ramanjulu Sunkar

3. Target Prediction Algorithms and Bioinformatics Resources for miRNA Studies
Colin Clarke, Niall Barron, Mark Gallagher, Michael Henry, Paula Meleady, Martin Clynes

4. The CHO miRNA Transcriptome
Matthias Hackl, Nicole Borth, Johannes Grillari

5. MicroRNAs as Engineering Targets: Pathway Manipulation to Impact Bioprocess Phenotypes
Joseph Shiloach, Aliaksandr Druz, Michael Betenbaugh

6. MicroRNAs for Enhancement of CHO Cell Proliferation and Stability: Insights from Neuroblastoma Studies
Raymond L. Stallings

7. MicroRNA Detection Methods for Mammalian Cell Lines and Their Applications in Therapeutic Protein Production
Nan Lin, Carol Kreader

8. Manipulating Levels of Specific MicroRNAs in Mammalian Cells
Carol Kreader, Nan Lin

Keywords: Biomedicine, Pharmaceutical Sciences/Technology, Genetic Engineering, Animal Genetics and Genomics